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TitlePediatric Liver Disease [electronic resource] / edited by M. M. Fisher, C. C. Roy
ImprintBoston, MA : Springer US : Imprint: Springer, 1983
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Descript IX, 296 p. online resource


This was an important Symposium in a rapidly developing field of interest. It was designed to draw attention to areas which have been neglected in standard hepatology textbooks and to review areas of controversy. It was also meant to help bridge the communication gap between hepatologists'caring for children and adults as well as between some areas of clinical and basic research. The Symposium was a substantial success. Unfortunately two of the twenty participants did not deliver a manuscript. The result is a publication which is late and which is not as complete as it should be. For this lateness and incompleteness the editors apoloยญ gize most sincerely--especially to those participants who delivered their manuscripts on time but even to those who delivered their manuยญ scripts late. perhaps the most noteworthy feature of this publication is the fact that material presented in May 1980 is by no means out of date. Apart from the section on Viral Hepatitis, one of the most rapidly evolving fields of medicine, the context of the Symposium remains disturbingly current. The neglect continues, the controversies remain. We hope that this publication will help draw investigators into liver research, provide a useful point of reference forยท those in the field and stand as a monument to editors past, present and future, who have chased, are chasing and will chase manuscripts in vain


Developmental Aspects of Liver Structure And Function -- Early Development of the Liver: a Review -- Developmental Aspects of the Hepatic Circulation -- Discussion -- Developmental Aspects of Bile Acid Metabolism and Hepatic Function -- Hepatic Drug-Metabolizing Enzymes during Embryonic and Fetal Development -- Discussion -- Cholestatic Liver Disease in Newborns and Infants -- A Clinical Approach to Cryptogenic Cholestasis of the Newborn -- Role of Bile Acids in Pediatric Cholestasis -- Microfilament Dysfunction in Cholestasis: Possible Involvement in Familial Pediatric Cholestatic Syndromes -- Discussion -- Extrahepatic Biliary Atresia: Clinical Aspects -- Pathology and Pathogenesis of Extrahepatic Biliary Atresia -- The Surgery of Biliary Atresia: Current Investigations -- Discussion -- New Developments in Viral Hepatitis -- Viral Hepatitis Type A: Redefinition of Virologie, Clinical and Epidemiologic Features -- Discussion -- Viral Hepatitis, Type B -- Hepatitis Non A Non B: A Newly Recognized Old Disease -- Discussion -- Metabolic Liver Disease -- Hereditary Fructose Intolerance -- Deficiency of Fumarylacetoacetase in the Acute Form of Hereditary Tyrosinemia with Reference to Prenatal Diagnosis -- A Metabolic Basis for Treatment of Type I Glycogen Storage Disease -- Discussion -- Wilsonโ{128}{153}s Disease โ{128}{148} Hepatolenticular Degeneration. The Importance of Early Diagnosis -- Alpha-1-Antitrypsin Deficiency -- Discussion -- Closing Remarks -- Contributors

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