Title | Contemporary Metabolism [electronic resource] : Volume 1 / edited by Norbert Freinkel |
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Imprint | Boston, MA : Springer US, 1979 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-3447-7 |
Descript | XXVI, 498 p. online resource |
1 Disorders of Purine and Pyrimidine Metabolism -- 1.1. Introduction -- 1.2. Purine Metabolism -- 1.3. Adenosine Deaminase Deficiency Associated with Severe Combined Immunodeficiency Disease -- 1.4. Purine Nucleoside Phosphorylase Deficiency -- 1.5. Biochemical Basis of the Immunodeficiency in Adenosine Deaminase and Purkie Nucleoside Phosphorylase Deficiency -- 1.6. Purine 5โ-Nucleotidase Deficiency in Hypogammaglobulinemia -- 1.7. Adenine Phosphoribosyltransferase Deficiency -- 1.8. Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency -- 1.9. Increased Phosphoribosyl-1-Pyrophosphate Synthetase Activity -- 1.10. Xanthinuria -- 1.11. Gouty Arthritis -- 1.12. Decreased Adenylate Deaminase Activity -- 1.13. Abnormalities of Pyrimidine Metabolism -- 1.14. Abnormalities of DNA Repair (Xeroderma Pigmentosum) -- 1.15. Purine and Pyrimidine Compounds as Inhibitors of Viral and Cellular Proliferation -- References -- 2 Metabolic Actions of Ethanol -- 2.1. Effects of Ethanol on Protein Metabolism -- 2.2. Effects of Ethanol on Lipid Metabolism -- References -- 3 Disorders of Lipid and Lipoprotein Metaboiism -- 3.1. Introduction -- 3.2. Lipoprotein Structure and Metabolism -- 3.3. Type III Hyperlipoproteinemia -- 3.4. Tangier Disease -- 3.5. High-Density Lipoprotein Levels and Coronary Heart Disease -- 3.6. Cholesterol Metabolism and Its Regulation -- 3.7. Familial Hypercholesterolemia -- 3.8. Chronic Renal Failure and Hyperlipidemia -- 3.9. Hypertriglyceridemia -- 3.10. Hyperlipidemia and Its Treatment -- References -- 4 Nutrition and Cellular Growth of the Brain -- 4.1. Methods for Producing Early Malnutrition -- 4.2. Malnutrition and Brain Size -- 4.3. Malnutrition and Cellular Growth of the Brain -- 4.4. Malnutrition and Myelination -- 4.5. Other Effects of Malnutrition on the Growing Brain -- 4.6. Regional Changes Induced by Malnutrition -- 4.7. Malnutrition and Cellular Growth of the Peripheral Nerves -- 4.8. Malnutrition and Cellular Growth of the Human Brain -- References -- 5 Metabolic Aspects of Renal Stone Disease -- 5.1. Introduction -- 5.2. Renal Stone Disease Secondary to Increased Crystalloid Excretion -- 5.3. Treatment of Renal Stone Disease -- References -- 6 Hormone Receptors, Cyclic Nucleotides, and Control of Cell Function -- 6.1. Introduction -- 6.2. Receptor Systems -- 6.3. Regulation of Adenylate Cyclase -- 6.4. Protein Kinases -- 6.5. Calcium Regulation of Cyclic Nucleotide Concentration -- 6.6. Cyclic Nucleotides in the Extracellular Fluids -- References -- 7 Diabetes Mellitus -- 7.1. Heterogeneity of Diabetes Mellitus -- 7.2. Insulin Secretion -- 7.3. Insulin Resistance and Insulin Receptors -- 7.4. Diabetes and Exercise -- 7.5. Diabetes and Pregnancy -- 7.6. Acidosis in Diabetes -- 7.7. Long-Term Complications -- 7.8. Treatment of Diabetes Mellitus -- References -- 8 Glucagon and Somatostatin -- 8.1. Anatomy of the Islets of Langerhans -- 8.2. Structure-Function Relationships of Glucagon -- 8.3. Pancreatic and Extrapancreatic Immunoreactive Glucagons -- 8.3.4. Immunoreactive Glucagon in Plasma -- 8.4. Glucagon Metabolism, Clearance, and Degradation -- 8.5. Actions of Glucagon -- 8.6. Control of Glucagon Secretion -- 8.7. Glucagonlike Immunoreactivity (Enteroglucagon) -- 8.8. Somatostatin -- 8.9. Glucagon in Clinical Medicine -- References -- 9 Recent Advances in Body Fuel Metabolism -- 9.1. Introduction -- 9.2. Glucose Metabolism -- 9.3. Ketone and Fatty Acid Metabolism -- 9.4. Amino Acid Metabolism -- 9.5. Fuel Metabolism in Exercise -- References -- 10 Whatโs New in Obesity: Current Understanding of Adipose Tissue Morphoiogy -- 10.1. Introduction -- 10.2. Techniques for Measuring Adipocyte Size and Number -- 10.3. Cellularity of Adipose Tissue in Man and Animals -- 10.4. How Constant Is Adipocyte Number? -- 10.5. How Are New Adipocytes Formed? -- 10.6. Significance of Cell Size and Number in Energy Regulation -- References -- 11 Divalent Ion Metabolism -- 11.1. Introduction -- 11.2. Vitamin D -- 11.3. Clinical Disorders That Involve Altered Vitamin D Metabolism -- 11.4. Phosphorus Metabolism -- References -- 12 Metabolism of Amino Acids and Organic Acids -- 12.1. Pyruvate Metabolism and Its Disorders -- 12.2. Pyruvate Metabolism and Its Regulation -- 12.3. Specific Disorders of Pyruvate Metabolism -- References