Title | Preimplantation Genetics [electronic resource] / edited by Yury Verlinsky, Anver Kuliev |
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Imprint | Boston, MA : Springer US, 1991 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-1351-9 |
Descript | 336 p. online resource |
I. Embryological Aspects of Preimplantation Genetics -- Oocyte Development -- Experimental Cytogenetics of Preimplantation Development -- Changing Physiological Systems in the Preimplantation Embryo -- II. Micromanipulation and Biopsy of Gametes and Preembryos -- Biopsy of Human Gametes -- Manipulation Techniques with Potential Use in Animal Agriculture -- Enhancement of Fertilization and Hatching Using Micromanipulation -- Biopsy of Human Cleavage Stage Embryos and Sexing by DNA Amplification -- Biopsy of Blastocyst -- III. Genetic Analysis of Gametes and Preembryos -- Chromosomal Analysis of Human Spermatozoa -- Chromosome Analysis of Oocytes and Embryos -- Preimplantation Diagnosis of Genetic Disease Using Enzyme Assays -- Single Sperm PCR Analysis-Implications for Preimplantation Genetic Disease Diagnosis -- Preimplantation Genetic Analysis Using PCR -- Co-amplification of X- and Y-Specific Sequences for Sexing Preimplantation Human Embryos -- In Situ Hybridization of Blastomeres from Embryo Biopsy -- IV. Clinical Aspects of Preimplantation Genetics -- In Vitro Fertilization and Preimplantation Diagnosis -- Uterine Lavage for Preimplantation Genetic Diagnosis -- Assessing Loss Rates in the Preimplantation Stages of Gestation -- Practical Considerations in Preimplantation Diagnosis -- V. Gene Expression in Preimplantation Development and Gene Therapy -- Evolutionary Analysis of Mammalian Homeobox Genes -- Gene Expression in Preimplantation Embryos -- Somatic Gene Therapy -- Strategies for Human Germ Line Gene Therapy -- VI. Ethical and Legal Aspects of Preimplantation Genetics -- Ethical Issues in the Control of Genetic Diseases -- Ethical and Selected Medical Aspects of Preimplantation Genetic Diagnosis -- Legal and Ethical Issues in Preimplantation Genetic Diagnosis -- VII. Technical Aspects of Preimplantation Genetics -- Techniques for Micromanipulation and Biopsy of Human Gametes and Preembryos -- Techniques for Microsurgical Fertilization -- Method for Obtaining Human Sperm Chromosomes -- Reliable Technique for Chromosomal Preparations from Mammalian Oocytes, Preimplantation Embryos and Isolated Blastomeres -- DNA Amplification of Y-Specific Repeat Sequences for Sexing Preimplantation Human Embryos -- DNA Analysis of Gametes and Embryos: Analysis of Delta-F508 Cystic Fibrosis Mutation in Single Cells -- Summary