Author | Tallarida, Ronald J. author |
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Title | Manual of Pharmacologic Calculations [electronic resource] : With Computer Programs / by Ronald J. Tallarida, Rodney B. Murray |
Imprint | New York, NY : Springer US, 1981 |
Connect to | http://dx.doi.org/10.1007/978-1-4684-0101-1 |
Descript | 150 p. online resource |
I: Computational Procedures -- 1. Dosage and Concentration: Drug Stock Solutions -- 2. Mean, Standard Deviation, and Confidence Limits -- 3. Linear Regression I -- 4. Linear Regression II: Lines through Origin -- 5. Analysis of the Regression Line -- 6. Parallel Lines I: Test for Parallelism -- 7. Parallel Lines II: Construction of Parallel Lines -- 8. Graded Dose-Response -- 9. Quantal Dose-Response: Probits -- 10. Relative Potency -- 11. Dissociation Constant I: Agonists -- 12. Dissociation Constant II: Partial Agonists -- 13. Dissociation Constant III: Perturbation Methods (Rate Constants in the Drug-Receptor Reaction) -- 14. pA2 Analysis I: Schild Plot -- 15. pA2 Analysis II: Time-Dependent Method -- 16. pA2 Analysis III: Constrained Plot -- 17. Enzyme Kinetics I: Michaelis-Menten Equation -- 18. Enzyme Kinetics II: Competitive Inhibition -- 19. Enzyme Kinetics III: Noncompetitive Inhibition -- 20. First-Order Drug Decay -- 21. Scatchard Plot -- 22. Henderson-Hasselbach Equation -- 23. Exponential Growth and Decay -- 24. Constant Infusion with First-Order Elimination -- 25. Multiple Intravenous Injections -- 26. Area under a Curve: Simpsonโs Rule and Trapezoidal Rule -- 27. Analysis of Variance -- 28. t-Test I: Grouped Data -- 29. t-Test II: Paired Data -- 30. Chi-Square Test -- 31. Dunnettโs Test (Comparison with a Control) -- 32. Mann-Whitney Test -- 33. Method of Litchfield and Wilcoxon: Confidence Limits of ED50 -- II: Computer Programs -- to Computer Programs -- S1 Dosage & Concentration: Drug Stock Solutions -- S2 Mean, Standard Deviation & Confidence Limits -- S3 Linear Regression I -- S4 Linear Regression II: Lines Through Origin -- S5 Analysis of the Regression Line -- S6 Parallel Lines I: Test for Parallelism -- S7 Parallel Lines II: Construction of Parallel Lines -- S8 Graded Dose-Response -- S9 Quantal Dose-Response: Probits -- S10 Relative Potency -- S11 Dissociation Constant I: Agonists -- S12 Dissociation Constant II: Partial Agonists -- S13 Dissociation Constant III: Perturbation Methods -- S14 pA2 Analysis I: Schild Plot -- S15 pA2 Analysis II: Time-Dependent Method -- S16 pA2 Analysis III: Constrained Plot -- S17 Enzyme Kinetics I: Michaelis-Menten Equation -- S18 Enzyme Kinetics II: Competitive Inhibition -- S19 Enzyme Kinetics III: Noncompetitive Inhibition -- S20 First-Order Drug Decay -- S21 Scatchard Plot -- S22 Henderson-Hasselbach Equation -- S23 Exponential Growth & Decay -- S24 Constant Infusion with First-Order Elimination -- S25 Multiple IV Injections -- S26 Area under a Curve: Trapezoidal & Simpsonโs Rules -- S27 Analysis of Variance -- S28 t-Test I: Grouped Data -- S29 t-Test II: Paired Data -- S30 Chi-Square Test -- S31 Dunnettโs Test -- S32 Mann-Whitney U-Test -- S33 Litchfield & Wilcoxon Test -- Appendix: Mathematical Tables