Title | Reproductive and Developmental Toxicity of Metals [electronic resource] / edited by Thomas W. Clarkson, Gunnar F. Nordberg, Polly R. Sager |
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Imprint | Boston, MA : Springer US, 1983 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-9346-1 |
Descript | XVIII, 846 p. online resource |
An Overview of the Reproductive and Developmental Toxicity of Metals -- Review Articles -- Effects of Metals on Male Reproduction -- Reproductive and Developmental Toxicity of Metals: Female Reproductive System -- The Congenital Teratogenicity and Perinatal Toxicity of Metals -- Effects of Metals: The Developing Central Nervous System -- Prenatal Metabolism: Metals and Metallothionein -- Effects and Metabolism of Toxic Trace Metals in the Neonatal Period -- Invited Papers -- Session 1. Effects of Metals on the Male Reproductive System -- Normal Testicular Structure and Methods of Evaluation under Experimental and Disruptive Conditions -- Effects of Environmental Metals on Male Reproduction -- Effects of Occupational Exposure to Lead on Sperm and Semen -- Cadmium and Reproduction: A Perspective After 25 Years -- Session 2. Effects of Metals on the Female Reproductive System -- Ovarian Toxicity: Effects on Sexual Maturation, Reproduction and Menopause -- Lead and Development of the Early Embryo -- Effect of Lead on Reproductive Capacity and Development of Mammals -- Spontaneous Abortion as Risk Indicator in Metal Exposure -- Session 3. Birth Defects and Perinatal Toxicity -- Metal-Induced Congenital Malformations -- Embryotoxicity and Teratogenicity of Nickel Compounds -- The Influence of Weight and Other Physiological Changes During Pregnancy and Lactation on the Toxicities of Mercury and Cadmium -- Ultrastructural and Biochemical Alterations of Cellular Organelles by Prenatal Exposure to Toxic Trace Metals -- Session 4. The Developing Central Nervous System -- Critical Processes in CNS Development and the Pathogenesis of Early Injuries -- Effects of Prenatal Methylmercury Poisoning upon Growth and Development of Fetal Central Nervous System -- Neurobehavioral Consequences of Early Exposure to Lead in Rhesus Monkeys: Effects on Cognitive Behaviors -- Central Nervous Effects of Perinatal Exposure to Lead or Methylmercury in the Monkey -- Developmental Toxicity of Metals: Implications for Public Health -- Session 5. Prenatal Aspects of the Metabolism of Metals -- The Placenta: Relevance to Toxicology -- Disposition of Metals in the Embryo and Fetus -- Heavy Metal Alterations of Placental Function: A Mechanism for the Induction of Fetal Toxicity in Cadmium -- Endogenous Metal-Binding Proteins in the Control of Zinc, Copper, Cadmium and Mercury Metabolism during Prenatal and Post-natal Development -- The Cellular Accumulation and Subcellular Localization of Metallothionein in Rat Liver during Postnatal Development -- Methylmercury Metabolism in Pregnant Mice: Its Modification by Selenium with Particular Reference to Prenatal Toxicity of These Compounds -- Session 6. Postnatal Aspects of the Metabolism of Metals -- Specific Features of Metal Absorption in Suckling Animals -- Are Developmental Changes in Methylmercury Metabolism and Excretion Mediated by the Intestinal Microflora? -- Trace Element Absorption in Infants: Potentials and Limitations -- Differences in Exposure and Metabolic Response of Infants and Adults to Lead, Cadmium and Zinc -- Special Topic Papers -- The International Programme on Chemical Safety in Relation to Reproductive and Developmental Toxicology -- Quality Control in Laboratories Testing for Environmental Pollution -- Participants -- Author Index