Title | Captopril and Hypertension [electronic resource] / edited by David B. Case, Edmund H. Sonnenblick, John H. Laragh |
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Imprint | Boston, MA : Springer US, 1980 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-9179-5 |
Descript | XII, 236 p. 11 illus. online resource |
I Humoral and Physiological Mechanisms in Hypertension -- 1Blood Pressure Homeostasis -- 2Mechanisms of Hypertension Induced by Electrolyte-Active Steroids -- 3The Relationship of the Renal Medulla to the Hypertensive State -- 4The Influence of Various Neurological Defects on the Release of Renin in Normal Man -- 5Angiotensin as a Determinant of Renal Perfusion and Function -- 6Systemic Vascular Resistance: Regulation and Effect on Left Ventricular Function -- II Angiotensin-Converting Enzyme: Its Role and Development of Inhibitors -- 7Physiological, Biochemical, and Immunologic Aspects of Angiotensin-Converting Enzyme -- 8Design of New Antihypertensive Drugs: Potent and Specific Inhibitors of Angiotensin-Converting Enzyme -- 9Captopril (Capotenยฎ; SQ 14,225) (D-3-Mercapto-2-methylpropanoyl-L-proline): A Novel Orally Active Inhibitor of Angiotensin-Converting Enzyme and Antihypertensive Agent -- 10Toxicologic and Drug Metabolic Studies of SQ 14,225 in Animals -- 11Captopril: An Oral Angiotensin-Converting Enzyme Inhibitor Active in Man -- III Clinical Use of Converting Enzyme Inhibitors -- 12The Renin System in High Blood Pressure, from Disbelief to Reality: Converting Enzyme Blockade for Analysis and Treatment -- 13Experiences with Blockade of the Renin System in Human Hypertension Using Converting Enzyme Inhibitor SQ 20,881 and Saralasin -- 14The Use of SQ 20,881 Converting Enzyme Inhibitor (Teprotide) for Diagnostic Purposes in Hypertension -- 15Clinical Experience with Blockade of the Renin-Angiotensin-Aldosterone System by an Oral Converting Enzyme Inhibitor (SQ 14,225, Captopril) in Hypertensive Patients