Title | Arterial Remodeling: A Critical Factor in Restenosis [electronic resource] / edited by Antoine Lafont, Eric J. Topol |
---|---|
Imprint | Boston, MA : Springer US : Imprint: Springer, 1997 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-6079-1 |
Descript | XXIX, 569 p. online resource |
1. Basis of the concept -- Restenosis: prevention of a complete stabilizing remodeling response following direct interventions on plaques -- Constrictive remodeling: do concepts of remodeling during chronic hypertension apply to restenosis? -- Growth and remodeling of coronary collateral vessels -- 2. Restenosis and remodeling: the facts -- Experimental evidence of remodeling after angioplasty -- Remodeling: accelerator or decelerator of luminal narrowing in human atherosclerotic arteries -- Histologic basis of vessel remodeling after various interventional procedures: a comparison of acute (cracks, breaks, tears, stretching) and chronic (tissue proliferation, recoil) changes -- Serial intravascular ultrasound evidence for arterial remodeling as a mechanism of restenosis following interventional coronary procedures -- Coronary blood flow during interventional procedures: implications for vascular remodeling -- 3. Restenosis and remodeling: the targets revisited -- Restenosis and remodeling: is the adventitia involved? -- Post-angioplasty smooth muscle cell apoptosis -- Intimal hyperplasia is the wrong target: restenosis as a failure of remodeling -- Endothelial dysfunction after angioplasty: a pathway for remodeling? -- 4. Molecular aspects of remodeling -- Vascular remodeling and lesion formation in restenosis: implications for nitric oxide-based therapeutics -- Oxidative stress and vascular remodeling -- Matrix metalloproteinases in injured artery -- Influence of angioplasty on matrix signalling and metabolism -- Intimal lesion growth: an assessment of important cellular events -- The effects of oxidized lipids and lipoproteins on arterial growth, remodeling and restenosis -- Oncogenes after angioplasty -- 5. Potential mechanisms -- Blood flow, shear stress and remodeling of the artery wall -- Inflammatory mechanisms of remodeling in injured arteries -- Effect of tensile stress in vascular remodeling -- 6. Remodeling: therapeutic aspects -- Coronary remodeling and interventional strategies -- Stent: a mechanical approach for remodeling inhibition -- Pharmacologic perspectives of remodeling inhibition -- Gene polymorphism and restenosis -- Gene transfer and vascular remodeling