Title | Genomic Instability and Immortality in Cancer [electronic resource] / edited by Enrico Mihich, Leland Hartwell |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1997 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-5365-6 |
Descript | X, 251 p. online resource |
1. Telomeres and Cell Division in Drosophila melanogaster -- 2. A Molecular Cytogenetic View of Chromosomal Heterogeneity in Solid Tumors -- 3. Cell Cycle Control of Genetic Stability -- 4. Aneuploidy and Heterogeneity Mechanisms in Human Colorectal Tumor Progression -- 5. p53-Dependent Signaling in Response to DNA Damage or Arrest of DNA Synthesis and its Role in Cell Cycle Control -- 6. Recombining DNA Damage Repair, Basal Transcription, and Human Syndromes -- 7. Telomere Length Regulation by the Pif1 DNA Helicase -- 8. Consequences of Mutations that Alter Telomeres in the Yeast K. lactis -- 9. Regulation of Telomere Length in Mammalian Cells -- 10. The DNA Damage Checkpoint -- 11. A Eukaryotic Cell Cycle -- 12. The Integration of Signalling Pathways in Mammalian Cells -- 13. Antitumor Drugs and Yeast Cell Cycle Checkpoints -- 14. Neoplastic Progression in Barrettโs Esophagus -- 15. E2F-1 Degradation by the Ubiquitin-Proteasome Pathway -- 16. Cdk4-Cyclin D1 and Cdk2-Cyclin E/A Phosphorylate Different Sites in the RB Protein -- 17. Cell Cycle Regulatory Proteins as Targets of Oncogenic Events