Title | Mechanisms of Environmental Mutagenesis-Carcinogenesis [electronic resource] / edited by Andreas Kappas |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1990 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-3808-0 |
Descript | XI, 283 p. online resource |
Mutations and Carcinogenicity -- Mutation Spectrum in Carcinogenicity -- Mechanisms of Chemically-Induced Genetic Effects on Molecular, Chromosomal and Cell Division Level -- Ultraviolet Light Mutagenesis in Bacteria: The Possible Role of a DNA Polymerase III Complex Lacking Proofreading Exonuclease -- Centromere Separation: Emerging Relationship with Aneuploidy -- Genetic Analysis of Genotoxic Effects on Chromosomes and Cell Division in Lower Eukaryotes -- DNA Repair and the Recombination Barrier between Divergent (Homologous) Chromosomes -- Consequences of Altering Tubulin Levels in Yeast -- A Genetic Assay Using Rodent/Human Hybrid Cells to Evaluate the Genotoxic Effects of Chemicals for Multiple Endpoints -- Aneuploidy in Humans -- Adaptability and Repair Mechanisms -- The Adaptive Response to Alkylation Damage in Escherichia coli -- The Adaptive Response of Human Lymphocytes to Radiation or Chemical Mutagens: Cross-Adaptation and Synergism -- Evolving Mutation Rates and Prospects for Antimutagenesis -- Genetic Analysis of DNA Repair Defect in Xeroderma Pigmentosum Cells: Identification of Complementing Genes -- Chemical Carcinogenesis-Oncogenes -- Outline of a Descriptive General Theory of Environmental Chemical Cancerogenesis - Experimental Threshold Doses for Tumor Promoters -- The Interaction of Steroid Hormones and Oncogenes in the Establishment of Malignancy -- The Relationship between DNA-Alkali-Labile Sites and Carcinogenesis in Mammalian Cells -- Structure and Metabolism of Mutagens-Carcinogens -- Quantitative Structure-Activity Relationships, and Mutagens and Carcinogens -- Enzymic Aspects on the Metabolic Activation of Aromatic and Heterocyclic Amine Mutagensin Mammalian and Bacterial Cells -- Biomonitoring and Epidemiology of Humans Exposed to Environmental Mutagens-Carcinogens -- Current Techniques for Human Population Monitoring for Genetic Effects -- Use of Aquatic Animals for Monitoring Genotoxicity in Unconcentrated Water Samples -- Cytogenetic Monitoring of Industrial Workers Exposed to Chemicals -- Monitoring Congenital Anomalies in Populations Exposed to Environmental Mutagens -- European Community Research on Genetic Effects of Environmental Chemicals and on Biomonitoring of Human Exposure -- Contributors