1 Biochemical, Immunological, and Molecular Markers of Hemopoietic Precursor Cells -- 1. Introduction -- 2. Biochemical Markers -- 3. Immunological Markers -- 4. Molecular Markers -- 5. Analysis of Human Hemopoietic Ontogenesis by Immunological and Molecular Markers -- 6. New Opportunities for Immunological and Molecular Markers: Minimal Residual Disease Detection and Therapeutical Approaches -- 7. References -- 2 Cell Surface Markers in Leukemia and Lymphoma -- 1. Introduction -- 2. B Cells -- 3. T Cells -- 4. Myeloid Cells -- 5. Summary -- 6. References -- 3 Cytoskeletal Organization of Normal and Leukemic Lymphocytes and Lymphoblasts -- 1. Introduction -- 2. Microfilaments in Normal and Leukemic Lymphocytes and Lymphoblasts -- 3. Intermediate-Size Filaments in Normal and Leukemic Lymphocytes and Lymphoblasts -- 4. Microtubules in Lymphoid Cells -- 5. Organization of Spectrin in Lymphocytes -- 6. Conclusions -- 7. References -- 4 Signaling Events in T-Lymphocyte-Dependent B-Lymphocyte Activation -- 1. Introduction -- 2. B-Cell Antigen Receptor-Mediated Signaling -- 3. Molecular Bases of T-Cell-Mediated B-Cell Signaling -- 4. Biological Evidence for Ia-Mediated Signal Transduction -- 5. Biochemical Evidence for Ia-Mediated Signal Transduction -- 6. Conclusions -- 7. References -- 5 IgE Receptors on Lymphocytes and IgE-Binding Factors -- 1. Introduction -- 2. Historical Overview -- 3. Fc?RII on Lymphocytes -- 4. IgE-Binding Factors -- 5. Glycosylation-Regulating Factors: GEF and GIF -- 6. Interleukin 4 and Gamma Interferon -- 7. CD23 Antigen -- 8. Conclusion -- 9. References -- 6 Lymphocyte-Mediated Cytolysis: Role of Granule Mediators -- 1. Role of Granules and Perform in Lymphocyte-Mediated Killing -- 2. Other Candidate Mechanisms of Lymphocyte-Mediated Killing -- 3. Resistance of Lymphocytes to Self-Mediated Killing -- 4. Conclusion -- 5. References -- 7 CR1โCytoskeleton Interactions in Neutrophils -- 1. Introduction -- 2. Detergent Extraction of Cells -- 3. ReceptorโCytoskeleton Interactions -- 4. The C3b Receptor (CR1) -- 5. References -- 8 The Flow of Granular Organelles in Leukocyte Differentiation -- 1. Introduction -- 2. Biogenesis of Membrane-Bound Organelles -- 3. Leukocyte Granules are Major Determinants of Function -- 4. Granules Interact with the Plasma Membrane -- 5. Pathology of Myeloid Granules and Plasma Membranes -- 6. Conclusion -- 7. References -- 9 The Elusive Oxidase: The Respiratory Burst Oxidase of Human Phagocytes -- 1. Introduction -- 2. The Respiratory Burst -- 3. The Activated NADPH Oxidase -- 4. Identification of Components of the Oxidase -- 5. Postulated Components of the NADPH Oxidase -- 6. Summary -- 7. References -- 10 Myeloperoxidase: Localization, Structure, and Function -- 1. Introduction -- 2. Background -- 3. Structure -- 4. Synthesis -- 5. Molecular Biology: The Myeloperoxidase Gene -- 6. Function -- 7. References -- 11 Mechanisms of Oxidase Activation in Neutrophils: Importance of Intracellular Calcium and Cytoskeletal Interactions -- 1. Importance of the Neutrophil Oxidase in Physiology and Pathology -- 2. The Neutrophil Oxidase -- 3. StimulusโOxidase Activation Coupling -- 4. Cytoskeletal Components and Neutrophil Activity -- 5. Actin Polymerization and Oxidase Activation -- 6. Conclusion -- 7. References -- 12 Neutrophil and Eosinophil Granules as Stores of โDefenseโ Proteins -- 1. Introduction -- 2. The Vacuolar Apparatus of Granulocytes -- 3. Defense Polypeptides of Granulocytes -- 4. Conclusions -- 5. References -- 13 Membrane Glycoproteins of Mast Cells and Basophils -- 1. Introduction -- 2. Receptors for Complement Anaphylatoxins on Mast Cells and Basophils -- 3. Immunoglobulin Receptors on Mast Cells and Basophils -- 4 Immunoglobulin E on Mast Cells and Basophils -- 5. Hemopoietic Lineage-Associated Membrane Glycoproteins of Mast Cells and Basophils -- 6. References

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