Title | Molecular and Cellular Biology of Prostate Cancer [electronic resource] / edited by James P. Karr, Donald S. Coffey, Roy G. Smith, Donald J. Tindall |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1991 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-3704-5 |
Descript | XII, 383 p. online resource |
I. Intracellular Communications -- Tissue Specificity and Cell Death are Associated with Specific Alterations in Nuclear Matrix Proteins -- Mechanism of Growth Regulation in Androgen Responsive Cells -- The Impact of Androgen, Extracellular Matrix, and Stroma upon Proliferation and Differentiation of Benign and Malignant Prostate Epithelial Cells -- Therapeutic Approaches to Activating Programmed Cell Death of Androgen-Independent Prostatic Cancer Cells -- Cell Motility and Structural Harmonics in Prostate Cancer -- II. Growth Factors - 1 -- Studies of the Endocrine and Paracrine Effect of Tumor Produced Factors in Human Genitourinary Cancers -- Fibroblast Growth Factor: Implications in the Etiology of Benign Prostatic Hyperplasia -- Fibroblast-Mediated Human Epithelial Tumor Growth and Hormonal Responsiveness In Vivo -- Polyamine Requirement of Prostate Cancer Cell Proliferation -- Heparin-Binding (Fibroblast) Growth Factor/Receptor Gene Expression in the Prostate -- Characterization and Partial Purification of a Non - Heparin-Binding Prostate Growth Factor From Cancerous Human Prostate -- Growth Factors - 2 -- Transforming Growth Factor a : A Potential Autocrine Growth Regulator in Prostatic Carcinoma -- Prostatic Growth Factors (PrGFs) โ From the Identification of Probasin to the Role of PrGFs -- Urogenital Sinus Derived Growth Inhibitory Factor -- Growth Factor Antagonists in Prostate Cancer: Suramin and Cytotoxic Polyamines as Potential Therapy -- Transforming Growth Factors in Human Prostate Cancer -- Gene Products as the Motivating Force in the Prostate Cellโs Response to Androgens -- III. Steroid Receptors -- Molecular Biology of Prostate - Specific Antigen -- Structure and Expression of the Androgen Receptor in Normal Tissues and in Prostate Carcinoma Cell Lines -- Structural Analysis and Gene Expression of TR2 Receptor and TR3 Receptor -- cDNA Cloning, Antibody Production and Immunohistochemical Localization of the Androgen Receptor -- New Approaches to Studies on the Androgen Receptor -- Specific Receptors for Vitamin D3 in Human Prostatic Carcinoma Cells -- IV. Poster Presentations -- Role of Androgens and Extracellular Matrix in the Growth and Differentiation of Benign and Malignant Prostatic Epithelial Cells -- Tissue Specificity and Cell Death Are Associated with Specific Alterations in Nuclear Matrix Proteins -- ElTect of Transformation on Rat Prostatic Fibroblasts: Alterations In Extracellular Matrix and Cytoskeleton Gene Expression with Retention of Androgen Responsiveness and Androgen Receptor Expression -- A Potential Role for the MDR-1 Gene in the Development of Androgen-Independent Tumors -- Relevance of Low Androgen Levels and Adrenal Androgens in the Growth of Transplantable Human Prostatic Carcinomas -- Growth-Stimulating Effect of Growth Factor(s) from Androgen Independent Tumor Cells (CS 2-Cell) on Androgen Responsive Tumor Cells -- The Cellular Form of Human Prostatic Acid Phosphatase May Function as a Phosphotyrosyl Protein Phosphatase in Cells -- Expression of Prostate Antigen in LNCaP Cells in Culture -- Allelic Expression of the Mouse Ren-1 Genes in the Anterior Prostate (Coagulating Gland) -- V. Dna Structure and Gene Expression -- Genomic Alterations in Prostatic Cancer -- Regulation of Gene Expression in the Prostate -- Androgen Regulation of HBGF I-(aFGF) and Characterization of the Androgen-Receptor mRNA in the Human Prostate Carcinoma Ceil Une - LNCaP/A-dep -- DNA Methylation, Differentiation and Cancer -- Evidence for tbe Involement of Genetic Differences and Mesenchymal Factors in the Progression of Oncogene - Induced Prostate Cancer in Reconstituted Mouse Prostate -- Differential Hybridization Analysis as a Tool to Study Prostatic Cancer Metastasis -- Molecular Biology of Androgen Acceptors in Prostatic Cancer Cells -- Panel Discussion -- Panel Discussion -- Panel Discussion -- Panel Discussion -- Panel Discussion -- Contributors