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TitleGenes, Oncogenes, and Hormones [electronic resource] : Advances in Cellular and Molecular Biology of Breast Cancer / edited by Robert B. Dickson, Marc E. Lippman
ImprintBoston, MA : Springer US : Imprint: Springer, 1992
Connect tohttp://dx.doi.org/10.1007/978-1-4615-3500-3
Descript XX, 446 p. online resource

SUMMARY

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diยญ agnosis, staging, markers, all forms of treatment modalities, basic biology, and more


CONTENT

I. The Progression of Node-Negative to -Positive Breast Cancer -- 1. Prognostic Factors in Axillary Node-Negative Breast Cancer -- 2. Role of Type IV Collagenases in Human Breast Cancer -- II. Suppressor Genes and Negative Growth Factors -- 3. Suppressor Genes in Breast Cancer: An Overview -- 4. The Role of the Retinoblastoma Gene in Breast Cancer Development -- 5. Mammary Derived Growth Inhibitor (MDGI) -- 6. Roles for Transforming Growth Factors-? in the Genesis, Prevention, and Treatment of Breast Cancer -- III. Oncogenes and Stimulatory Growth Factors -- 7. Mechanisms Involving an Expanding erbB/EGF Receptor Family of Tyrosine Kinases in Human Neoplasia. -- 8. c-erbB2 Amplification and Overexpression in Human Tumors -- 9. Clinical Significance of c-erbB2B2 Protein Overexpression -- Anti-p185HER2 Monoclonal Antibodies: Biological Properties and Potential for Immunotherapy193 -- 11. A Chimeric EGFR/neu Receptor in Studies of neu Function -- 12. Involvement of Protein Kinase C in the Growth Regulation of Human Breast Cancer Cells -- 13. Tyrosine Kinase Receptor โ{128}{148} Nuclear Protooncogene Interactions in Breast Cancer -- IV. Steroid Hormone Receptors -- 14. Characterization and Regulation of Estrogen and Progesterone Receptors in Breast Cancer -- 15. Estrogen and Progesterone Receptor Structure and Action in Breast Cancer Cells -- 16. Progesterone Receptors in Breast Cancer -- V. Differentiation and Function of Epithelium and Stroma in the Breast -- 17. Intermediate Filament Protein Expression in Normal and Malignant Human Mammary Epithelial Cells -- 18. Casein Gene Expression: From Transfection to Transgenics -- 19. The Whey Acidic Protein -- 20. Stromal-Epithelial Interactions in Breast Cancer


Medicine Cancer research Oncology Medicine & Public Health Oncology Cancer Research



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