Title | Retinal Degeneration [electronic resource] : Clinical and Laboratory Applications / edited by Joe G. Hollyfield, Robert E. Anderson, Matthew M. LaVail |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1993 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-2974-3 |
Descript | XIV, 365 p. online resource |
I. The Macula, Aging and Macular Degeneration -- Lipofuscin in Aged and AMD Eyes -- Retinoid Reaction Products in Age Related Retinal Degeneration -- How Many Cones Are Required to โSeeโ?: Lessons from Stargardtโs Macular Dystrophy and from Modeling with Degenerate Photoreceptor Arrays -- The Genetics of Age-Related Maculopathy -- Linkage Analysis in Malattia Leventinese, an Autosomal Dominant Form of Macular Degeneration -- Mutations in the Human Retinal Degeneration Slow (RDS) Gene Can Cause Either Retinitis Pigmentosa or Macular Dystrophy -- II. Retinitis Pigmentosa and Allied Retinal Degenerations: Molecular, Cellular and Clinical Studies -- Extensive Genetic Heterogeneity in Autosomal Dominant Retinitis Pigmentosa -- Genetic and Epidemiological Study of Autosomal Dominant (ADRP) and Autosomal Recessive (ARRP) Retinitis Pigmentosa in Sardinia -- Clinical Features of Autosomal Dominant Retinitis Pigmentosa Associated with the Gly-188-Arg Mutation of the Rhodopsin Gene -- Ocular Findings in Patients with Autosomal Dominant Retinitis Pigmentosa Due to a 3-Base Pair Deletion at Codon 255/256 of the Human Rhodopsin Gene -- Phenotypes of Carboxyl-Terminal Rhodopsin Mutations in Autosomal Dominant Retinitis Pigmentosa -- Heterogeneity of Usher Syndrome Type I -- The Norrie Disease Gene: Positional Cloning, Mutation Analysis and Protein Homologies -- Clinical and Genetic Heterogeneity of Leberโs Congenital Amaurosis -- Studies toward the Isolation of the RP3 Gene -- Comments on Gene Symbols and Terminology -- Identification of Candidate Genes for Eye Diseases: Studies on a Neural Retina-Specific Gene Encoding a Putative DNA Binding Protein of Leucine Zipper Family -- Nonradioactive Single Strand Conformation Polymorphism (PCR-SSCP): A Simplified Method Applied to a Molecular Genetic Screening of Retinitis Pigmentosa -- Retinopathia Pigmentosa Plus- The Value of Ultrastructural Examination of the Human Retina -- III. Studies of Retinal Degeneration Using Transgenic Mice and Other Animal Models -- Simulation of Autosomal Dominant Retinitis Pigmentosa in Transgenic Mice -- Creating Transgenic Mouse Models of Photoreceptor Degeneration Caused by Mutations in the Rhodopsin Gene -- A Molecular Characterization of the Retinal Degeneration Slow (rds) Mouse Mutation -- Transgenic Mouse Studies of Retinal Degeneration: Expression of the ร-Subunit of cGMP Phosphodiesterase and Transducin ?-Subunits -- Retinal Development under the Influence of SV40 T-Antigen in Transgenic Mice -- Nonsense Mutations in the ? Subunit Gene of the Rod cGMP Phosphodiesterase that Are Associated with Inherited Retinal Degenerative Disease -- Systemic Alterations in Docosahexaenoic Acid Metabolism in Inherited Retinal Degenerations -- Variable Expressivity of rd-3 Retinal Degeneration Dependent on Background Strain -- Retinal Degenerations in the Briard Dog -- IV. Agents Which Cause or Prevent Retinal Degeneration -- Growth Factors as Possible Therapeutic Agents for Retinal Degeneration -- Laser Effects on Photoreceptor Degeneration in the RCS Rat -- Role of Heat Shock Protein 70 (HSP70) in Photoreceptor Cell Survival in the Aged Rat -- A Morphometric and Immunopathologic Study of Retinal Photic Injury in Primate -- Cutaneous Melanoma-Associated Retinopathy -- The Effect of Naphthalene on the Retina of Rabbit -- Biological Effects of Retinoids and Retinoid Metabolism in Cultures of Chick Embryo Retina Neurons and Photoreceptors