Title | Anticancer Drug Discovery and Development: Natural Products and New Molecular Models [electronic resource] : Proceedings of the Second Drug Discovery and Development Symposium Traverse City, Michigan, USA โ June 27-29, 1991 / edited by Frederick A. Valeriote, Thomas H. Corbett, Laurence H. Baker |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1994 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-2610-0 |
Descript | XI, 403 p. online resource |
1. Discovery of Natural Products from Microalgae and Marine Organisms -- 2. Discovery of Naturally Occurring Antitumor Agents -- 3. Marine Invertebrates and Microbes as Sources of Potential Antitumor Compounds -- 4. Novel Strategies for the Discovery of Plant-Derived Anticancer Agents -- 5. A Strategy for Identifying Novel Inhibitors of DNA Topoisomerase I -- 6. Altromycins: A New Family of Antitumor Antibiotics-Discovery and Biological Evaluation -- 7. Suppression of Human Melanoma Metastasis in Scid Mice with Antibodies to the EGF-Receptor -- 8. Growth Factor and Oncogene Signalling as a Target for Anticancer Drug Development -- 9. Nucleoside and Nucleotide Modulation of Oncogenic Expression: A New Approach to Cancer Chemotherapy -- 10. Interferons in Cancer Therapy: from Clinical Trials to New Potentials in Anticancer Drug Discovery and Development -- 11. Selection and Manipulation of Immunoglobulins for Radionuclide Delivery -- 12. Microorganisms: Strategic Sources of Novel anti-Tumor Agents -- 13. The Therapeutic Potential of Novel Pure Antiestrogens -- 14. Preclinical Pharmacology and Phase I Clinical Trials of Taxotere (Rp 56976, Nsc 628503) -- 15. Bropirimine, A Small-Molecule Biological Response Modifier and an Effective Antitumor Agent -- 16. Determinants of Etoposide Cytotoxicity in Vitro -- 17. Screening for Anticancer Leads from Marine Organisms in a Mechanism-Based Drug Discovery Program