Title | Mammary Tumorigenesis and Malignant Progression [electronic resource] : Advances in Cellular and Molecular Biology of Breast Cancer / edited by Robert B. Dickson, Marc E. Lippman |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 1994 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-2592-9 |
Descript | XIV, 361 p. online resource |
I. Proliferation, Differentiation, and Malignant Progression -- 1. Morphological and biological observations relating to the development and progression of breast cancer -- 2. Growth, differentiation, and transformation of human mammary epithelial cells in culture -- II. Genetic Basis for Cancer Onset and Progression -- 3. Genetic analysis of breast and ovarian cancer in families -- 4. The p53 tumor-suppressor gene in human breast cancer -- 5. Tumor-suppressor genes in breast cancer progression -- 6. Estrogen receptor variants in breast cancer -- 7. Hormone โresistanceโ in breast cancer: the role of normal and mutant steroid receptors -- III. Growth Factors, Receptors, and Polyamines -- 8. The epidermal growth factor family in the mammary gland and other target organs for ovarian steroids -- 9. Molecular and clinical aspects of the Neu/ErbB-2 receptor tyrosine kinase -- 10. MDGF1: a multifunctional growth factor in human milk and human breast cancer -- 11. The role of polyamines in the hormonal control of breast cancer cell proliferation -- IV. Cancer Cell Adhesion, Migration, and Proteolysis -- 12. Modulations of the epithelial phenotype during embryogenesis and cancer progression -- 13. Cell-cell adhesion in invasion and metastasis of carcinomas -- 14. Enhancement of tumor growth by basement membrane: modulation of growth and angiogenesis by laminin-derived synthetic peptides -- 15. Fetal-like fibroblasts: their production of migration-stimulating factor and role in tumor progression -- 16. Urokinase plasminogen activator (uPA) and its type inhibitor (PAI-1): regulators of proteolysis during cancer invasion and prognostic parameters in breast cancer -- V. Rodent Model Systems of Breast Cancer -- 17. Molecular mechanisms of chemical carcinogenesis in rodent models -- 18. Fgf-3, an oncogene in murine breast cancer