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TitleCardiac Energetics: From Emax to Pressure-Volume Area [electronic resource] / edited by Martin M. LeWinter, Hiroyuki Suga, Matthew W. Watkins
ImprintBoston, MA : Springer US : Imprint: Springer, 1995
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Descript XII, 240 p. online resource


Most of the progress in cardiac energetics in recent years has been spurred by the pressure-volume area concept, the natural extension into energetics of earlier pioneering work delineating the time-varying elastance framework for ventricular contraction. The book draws together a broad spectrum of researchers - basic, applied and clinical - having a shared interest in the energetics of cardiac muscle and ventricle, providing an overview of the current state of the art


1. Energy Costs of PVA and Emax: Constancy and Variability -- 2. Kinetic Property of Cardiac Myosin In Vitro1 -- 3. Thin Filament Regulation and Cardiac Energetics -- 4. Explaining Load-Dependent Ventricular Performance and Energetics Based on a Model of E-C Coupling -- 5. Cardiac Contractions, PVA and Energetic Considerations Determined from a Cardiac Muscle Crossbridge Model -- 6. Normalization of Emax and PVA -- 7. Observations on the Relation of PVA and MVO2 in Closed Chest Dogs -- 8. Regional Myocardial Contraction Coupled with Energetics -- 9. Energetics During Ventricular Fibrillation -- 10. Influence of Preload on Non-Mechanical VO2 Assessed with 2,3-Butanedione Monoxime -- 11. Emax and Myocardial Microcirculation -- 12. Efficiency of Ventricular-Arterial Coupling and Baroreflex Regulation of Blood Pressure -- 13. Ventriculo-Arterial Load Matching of Failing Hearts -- 14. Calcium Signaling and Pharmacology of Cardiotonic Agents -- 15. Effect of Inotropic Agents on Mechanoenergetics in Human Diseased Heart -- 16. Effects of Various Inotropic Agents on the Relation Between Ventriculoarterial Coupling and Myocardial Energetics in Patients with Idiopathic Dilated Cardiomyopathy

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