Title | Cardiovascular Genomics: New Pathophysiological Concepts [electronic resource] : Proceedings of the 2001 European Science Foundation Workshop in Maastricht / edited by Pieter A. Doevendans, Stefan Kรครคb |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 2002 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-1005-5 |
Descript | XIX, 275 p. online resource |
1. Genomics and clinical cardiology: Hype or hope? -- Session 1: Gene expression analysis -- 2. Salt-sensitive hypertension: Identification of downstream renal targets in the aldosterone-signaling pathway by Serial Analysis of Gene Expression (SAGE) -- 3. Cardiovascular proteomics: Effect of hypoxic conditions -- 4. Using comparative genome analysis to find interaction partners for frataxin -- Session 2: Genomics and pathophysiology of atherosclerosis -- 5. In vitro-in vivo gene expression analysis in atherosclerosis -- Session 3: Genomics in hypertension -- 6. Human essential hypertension: Role of the genes of the renin aldosterone system -- 7. Gene therapy for hypertension: Future or fiction? -- 8. Hormones and signalling pathways -- 9. Endothelial changes in hypertension -- Session 4: Genomics in cardiac hypertrophy and failure -- 10. Towards elucidation of genetic pathways in cardiac hypertrophy: Technique to develop microarrays -- 11. Gene expression in cardiac hypertrophy and failure: Role of G protein-coupled receptors -- 12. Little mice with big hearts: Finding the molecular basis for dilated cardiomyopathy -- 13. Cardiac hypertrophic signaling the good, the bad and the ugly -- Session 5: Molecular remodelling in arrhythmias -- 14. Ion channel regulation: From arrhythmias to genes to channels (to cures?) -- 15. Differential expression and functional regulation of delayed rectifier channels -- 16. Genetic polymorphisms and their role in ventricular arrhythmias -- 17. Molecular mechanisms of remodeling in human atrial fibrillation -- 18. G-protein ร3-subunit polymorphism and atrial fibrillation -- Session 6: Towards cellular transplantion -- 19. Human stem cell gene therapy -- 20. Towards human embryonic stem cell derived cardiomyocytes -- 22. Cellular cardiac reinforcement -- 23. Appendix to session 3 hypertension Adducin paradigm: An approach to the complexity of hypertension genetics