Title | BloodโBrain Barrier [electronic resource] : Drug Delivery and Brain Pathology / edited by David Kobiler, Shlomo Lustig, Shlomo Shapira |
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Imprint | Boston, MA : Springer US : Imprint: Springer, 2001 |
Connect to | http://dx.doi.org/10.1007/978-1-4615-0579-2 |
Descript | XII, 434 p. online resource |
1. Overview of the Structure and Function of the Blood-Brain Barrier in vivo -- 2. Expression and Modulation of Blood-Brain Monocarboxylate Transporters -- 3. Neuroprotective and Detoxifying Mechanisms at the Blood-Brain Interfaces -- 4. Measurement and Prediction of Blood-Brain Barrier Permeability: In vivo, in silico and in vitro approaches -- 5. Recent Advances in the Development of Cell Culture Models for the Blood-Brain and Blood-CSF-Barrier -- 6. Gene Expression Changes and Progression to a BBB Phenotype in a Dynamic Model of the BBB -- 7. Novel Endothelial-Mediated Responses Associated with Micro-Circulation and BBB function -- 8. Modulators of Blood-Brain Barrier (BBB) Permeability: In Vitro and In Vivo Drug Transport to the Brain -- 9. Controlled Modulation of the Blood-Brain and Blood-Tumor Barrier Using Novel Lipid Mimetic Compounds -- 10. Carbon Dioxide Gas as an Angiographic Contrast Agent in the Cerebral Circulation -- 11. Diffusion MRI and Q-Space Diffusion MRI: From Cerebral Ischemia to Multiple Sclerosis and Beyond -- 12. Brain Iron Uptake and Transport in Animal Model of Iron Deficiency, Tardive Dyskinesia and Neurodegenerative Diseases -- 13. Stress, Pyridostigmine and the Blood-Brain Barrier -- 14. Transcytosis and Signalling of Pneumococci at the Blood-Brain Barrier -- 15. Entry of Viruses into the Central Nervous System -- 16. An Animal Model for the Study of BBB Modulators -- 17. Physiological Pathways Responsible for the Breakdown of the Blood-Brain Barrier During Viral Encephalitis -- 18. Gene Transfer to the Salivary Glands: Application in Gene Therapy -- 19. The Effect of Hyperosmotic Blood-Brain Barrier Disruption on Experimental Autoimmune Encephalomyelitis -- 20. Direct In Vivo Evidence for ?4-Integrin Mediated Interaction of Encephalitogenic T Cells with Endothelial VCAM-1 in the Spinal Cord White Matter Using Intravital Fluorescence Videomicroscopy -- 21. The Blood-Brain Barrier in Immune Mediated Diseases of the Central Nervous System -- 22. Strategies for Increasing Drug Delivery to the Brain: Lessons Derived from Treatment of Brain Tumors -- 23. Intraarterial Therapy With or Without Radiation Therapy for Patients with Brain Tumors -- 24. Optimizing Drugs for Brain Action -- 25. The Role of Plasma Protein Binding in Drug Delivery to Brain -- 26. Issues Related to Intranasal Delivery of Neuropeptides to Temporal Lobe Targets -- 27. Synthesis of Poly(Carboxyphenoxypropane-Sebacic Anhydride) for the Delivery of Drugs to the Brain -- 28. Intranasal Delivery of Bioactive Peptides or Peptide Analogues Enhances Spatial Memory and Protects Against Cholinergic Deficits -- 29. Role of Inflammation in Stroke: Benefits or Harm? -- 30. Variations in Neuropathology and Pathophysiology Over Time and Among Areas in a Rat Model of Focal Areas in a Rat Model of Focal Cerebral Ischemia -- 31. Impairment and Pharmacological Protection of the Blood-Brain Barrier After Head Trauma -- 32. Pathophysiology of the Blood-Spinal Cord Barrier in Spinal Cord Injury