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AuthorWillis, William D. author
TitleSensory Mechanisms of the Spinal Cord [electronic resource] : Volume 1 Primary Afferent Neurons and the Spinal Dorsal Horn / by William D. Willis, Richard E. Coggeshall
ImprintBoston, MA : Springer US : Imprint: Springer, 2004
Edition Third Edition
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Descript XXIII, 581 p. online resource


The third edition of this monograph continues to have the goal of providing an overview of current thought about the spinal cord mechanisms that are responsible for sensory processing. We hope that the book is of value to both basic and clinical neuroscientists. Several changes have been made in the presentation, as well as additions because of the research advances that have been made during the past decade. Chapters 3 and 4 in the previous edition have been subdivided, and now the morphology of primary afferent neuยญ rons of the dorsal root ganglia is described in Chapter 3 and the chemical neuroanatomy 4. The description of the dorsal hom in the previous Chapter 4 of these neurons in Chapter is now included in Chapter 5, and the chemical neuroanatomy of the dorsal hom in Chapter 6. Furthermore, discussions of the descending control systems have now been of Chapter 12. consolidated at the end The authors would like to express their appreciation for the help provided by several individuals. R.E.C. wishes to acknowledge the many things he learned about primary afferent neurons from conversations with Dr S. N. Lawson. He also thanks Lyn Shilling for her assistance with the typing. WDW thanks Dr Nada Lawand for her critical reading of parts of the manuscript, Rosaline Leigh for help with the manuscript, and Griselda Gonzales for preparing the illustrations


1: Introduction -- Sensory Modalities and Channels -- Specificity versus Pattern Theories of Sensation -- Somatosensory System Dualities -- Conclusions -- 2: Sensory Receptors and Peripheral Nerves -- Composition of Peripheral Nerves -- Sensory Receptors -- Cutaneous Receptors -- Muscle Receptors -- Joint Receptors -- Visceral Receptors -- Conclusions -- 3: Dorsal Root Ganglion Cells and their Processes -- Dorsal Root Ganglion Cell Bodies -- Dorsal Root Ganglion Cell Processes -- Conclusions -- 4: Chemical Anatomy of Dorsal Root Ganglion Cells -- Amines -- Amino Acids -- Channels -- Enzymes -- Hormones -- Peptides -- VIP -- Proteins -- Receptors -- Conclusions -- 5: Structure of the Dorsal Horn -- Lamina I -- Lamina II (The Substantia Gelatinosa) -- Lamina III -- Lamina IV -- Lamina V -- Lamina VI -- Conclusions -- 6: Chemical Anatomy of the Dorsal Horn -- Amines -- Amino Acids -- Channels -- Enzymes -- Hormones -- Peptides -- Opioids -- Proteins -- Receptors -- Conclusions -- 7: Functional Organization of Dorsal Horn Interneurons -- Electrophysiological Recordings from Interneurons -- Population Responses -- Afferent Projections to the Dorsal Horn -- Responses to Electrical Stimulation -- Responses to Natural Stimulation -- Classification of Dorsal Horn Interneurons -- Dorsal Horn Neurons in Unanesthetized, Behaving Animals -- Pharmacology of Dorsal Horn Interneurons -- Inhibitory Transmitters in the Dorsal Horn -- Modulation of the Responses of Dorsal Horn Neurons -- Inhibitory Receptive Fields -- Models of Human Disease -- Genetic Influences on Spinal Cord Sensory Processing -- Conclusions -- References

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