Thyroid carcinoma is an uncommon malignanยญ ing the available non-human lines, as models cy. In the vast majority of patients, if treated for cell cycle studies and oncogene/antiยญ appropriately, it is associated with a benign oncogene regulation, because they are unaware clinical course. Why then does it hold a conยญ of the often fundamental dichotomy between tinuing fascination for so many physicians? thyroid malignancy and prognosis. Third, the The answer is probably directly dependent very nature of the benign clinical course has suggested to the major health research fundยญ on the very benign nature of most thyroid ing agencies that thyroid cancer is not worthy maligllancies. While there are terrible excepยญ of study in a time of scarce resources. tions, the follicular and papillary thyroid canยญ Nothing could be further from the truth. cers behave in a way quite alien to "common" This gratifying clinical course is the very reason neoplasia, since they grow and metastasize why the study of human thyroid cancer has the slowly. We believe that if only we could underยญ potential for contributing further to our funยญ stand such a transformed state, we would be able to learn a great deal about the normal and damental understanding of malignancy and, abnormal regulation of the cell cycle and imยญ perhaps more importantly, the mechanisms by prove our understanding of cancer. which the human body can resist neoplastic However, recent advances in the biology of cells
CONTENT
1. Papillary Thyroid Carcinoma -- 2. Follicular Carcinoma of the Thyroid -- 3. Radiation-Induced Thyroid Carcinoma -- 4. Thyroid Cancer in the Pediatric Patient -- 5. Surgery for Well-Differentiated Thyroid Carcinoma -- 6. Thyroglobulin -- 7. Radioactive Iodine Treatment of Thyroid Carcinoma -- 8. Medullary Carcinoma of the Thyroid -- 9. Anaplastic Thyroid Carcinoma -- 10. Lymphoma of the Thyroid Gland -- 11. Carcinoma Metastatic to the Thyroid Gland -- 12. External Radiation Treatment for Thyroid Carcinoma -- 13. Chemotherapy of Advanced Thyroid Cancer
