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TitleThe Kidney and Body Fluids in Health and Disease [electronic resource] / edited by Saulo Klahr
ImprintBoston, MA : Springer US : Imprint: Springer, 1983
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Descript XXI, 593 p. online resource


This volume was designed as a text for medical students, house officers, and even clinicians. It deals with the most common problems in nephrology, providing new insight into how to improve clinical skills. A comprehensive overview of renal physiology and electrolyte disorders lays the groundwork for a clear presentation of the pathophysiological principles that underlie these disorders and a step-by-step presentation of the mechanisms behind the signs and symptoms of kidney failure. The origins of this book can be traced to the teaching of a Renal Pathophysiology course at the Washington University School of Medicine, beginning in the mid-1960s. When changes in the medical school curriculum took place in the early 1970s, an effort was made to synthesize the minimum core curriculum for sophomore medical students, and the distillation of "essential material" to be covered in the area of renal pathophysiology led to the development of the first edition of a renal syllabus. This syllabus has been used in our department since 1974, and, following some of the recommendations and critiques of students and faculty, it has been entirely reworked many times to improve its effectiveness and value. This book is a direct extension of that syllabus, integrated with contriยญ butions from faculty members in our Renal Division, and expanded to include a section on therapy in most chapters. It is our hope that this format will serve the needs of not only sophomore and senior medical students, but also house officers, nephrology fellows, and clinicians


I. Basic Concepts of Fluid, Electrolyte, and Renal Physiology -- 1. Introduction to the Physiology of Body Fluids -- 2. Homeostatic and Excretory Functions of the Kidney -- 3. Nonexcretory Functions of the Kidney -- II. Pathophysiology of Fluid and Electrolyte Disorders -- 4. Pathophysiology of Volume Regulation and Sodium Metabolism -- 5. Edema and Edema-Forming States -- 6. The Pathophysiologic Bases for Aherations in Water Balance -- 7. Pathophysiology of Potassium Metabolism -- 8. Pathophysiology of Acid-Base Metabolism -- 9. Pathophysiology of Calcium, Magnesium, and Phosphorus Metabolism -- III. Pathophysiology of Hypertension -- 10. Pathophysiology of Hypertension -- IV. Pathophysiology of Proteinuric Renal Disease -- 11. Proteinuria and the Nephrotic Syndrome -- 12. Pathology and Pathophysiology of Proteinuric Glomerular Disease -- V. Renal Failure -- 13. Pathophysiology of Acute Renal Failure -- 14. Pathophysiology of Chronic Renal Failure -- 15. Pathophysiological Principles in the Treatment of Patients with Renal Failure -- VI. Pathophysiology of Nephrolithiasis -- 16. Pathophysiology of Nephrolithiasis -- VII. Renal Pharmacology -- 17. Renal Pharmacology

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