Title | Mechanisms of Cancer Metastasis [electronic resource] : Potential Therapeutic Implications / edited by Kenneth V. Honn, William E. Powers, Bonnie F. Sloane |
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Imprint | Boston, MA : Springer US, 1986 |
Connect to | http://dx.doi.org/10.1007/978-1-4613-2635-9 |
Descript | XVI, 428 p. online resource |
1. The Cancer Problem Today -- 2. Present Status and Future Prospects for Treatment of Metastatic Cancer -- 3. A Critical Overview of the Metastatic Process -- 4. Experimental Models for Studying the Pathogenesis and Therapy of Metastatic Disease -- 5. Problems Posed for Cancer Treatment by Tumor Cell Heterogeneity -- 6. Multidrug Resistance and Metastasis -- 7. Polyamine Biosynthesis: A Target for Antimetastatic Therapy -- 8. Chemical Mechanisms of Modulation of Tumor Growth and Metastasis by Prostaglandins -- 9. Platelet-Tumor Cell Interactions as a Target for Antimetastatic Therapy -- 10. Mechanisms of Inhibition of Cancer Dissemination by Warfarin -- 11. Cancer Cell Procoagulants and Their Possible Role in Metastasis -- 12. Role of Growth Stimulatory Factors in Determining the Sites of Metastasis -- 13. Interleukins, Lymphokines and Lymphoid Neoplasia -- 14. The Use of Activated Macrophages for the Destruction of Heterogeneous Metastasis -- 15. Biological Response Modifiers as Activators of Natural Killer Cells: Potential Role in Treatment of Metastasis -- 16. Breast Cancer Diagnosis with Human Mammary Epithelial Antigens and the Prospective Use of Antibodies Against Them in Therapy -- 17. Chemotaxis in Tumor Cells: Possible Mechanisms and Their Implications for Therapy -- 18. Invasion of Vascular Endothelium and Organ Tissue in Vitro by B16 Melanoma Variants -- 19. Domains of Laminin and Basement Membrane Collagen which Play a Role in Metastases -- 20. Interaction of Malignant Cells with Substrata: Adhesion, Degradation and Migration -- 21. Proteolytic Enzymes in Tumor Invasion and Degradation of Host Extracellular Matrices -- 22. Cathepsin B-Like Cysteine Proteinases and Metastasis -- 23. Applications for Antimetastatic Therapies