Title | Biotechnology in blood transfusion [electronic resource] : Proceedings of the Twelfth Annual Symposium on Blood Transfusion, Groningen 1987, organized by the Red Cross Blood Bank Groningen-Drenthe / edited by C. Th. Smit Sibinga, P. C. Das, L. R. Overby |
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Imprint | Boston, MA : Springer US, 1988 |
Connect to | http://dx.doi.org/10.1007/978-1-4613-1761-6 |
Descript | XIV, 258 p. online resource |
I. Fundamentals of biotechnology -- Opportunities for biotechnology in transfusion medicine -- to molecular genetics and recombinant DNA technology -- Molecular genetic analysis of HLA class II polymorphism -- Bioengineering in blood transfusion medicine -- Discussion -- II. Laboratory application of biotechnology -- Biotechnology in glood group serology โ Application and trends for the future -- The characterization of monoclonal antibodies directed against carbohydrate epitopes by immunochemical means; the importance of such monoclonal antibodies for the recognition of blood group antigens -- Biochemistry of HLA-B27 in transfected cells and transgenic mice -- Biotechnology in the development of HIV diagnostic procedures -- Biotechnology and the development of HBV diagnostic procedures -- Monoclonal antibodies in blood coagulation -- Discussion -- III. Biotechnology and blood components -- Monoclonal antibodies in the production of purified proteins from human plasma -- Production of clotting factors through biotechnology -- Mammalian cell expression and characterization of recombinant human antitrhombin III -- Production and testing of rDNA hepatitis B vaccine -- Production and application of monoclonal antibodies in T-cell depletion of bone marrow for transplantation -- LAK cell production: Application of rDNA and cell culture technology -- Biotechnology of hemopoietic cells in culture -- Discussion -- IV. Clinical application and future directions -- Use of gene probes for carrier detection and prenatal diagnosis in hemophillia A -- In vivo characteristics of rDNA Factor VIII: The impact for the future in hemophilia care -- Clinical experience with monoclateยฎ, a monoclonal antibody purified Factor VIII preparation from human plasma -- Depletion of lymphocytes from bone marrow โ indications, expectations and clinical experience -- Hematopoietic hormones in transfusion medicine -- Discussion