Title | Silent Myocardial Ischemia [electronic resource] : Proceedings of the Symposium on New Drugs and Devices October 15-16, 1987, Philadelphia, Pennsylvania / edited by Joel Morganroth, E. Neil Moore |
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Imprint | Boston, MA : Springer US, 1988 |
Connect to | http://dx.doi.org/10.1007/978-1-4613-1745-6 |
Descript | XIV, 242 p. online resource |
I Epidemiology, Pathophysiology, Classification -- 1. Epidemiology and prevalence of silent myocardial ischemia, and prognosis in asymptomatic patients -- 2. Pathophysiology of ischemia: Why are some episodes silent? -- 3. Myocardial ischemia as a useful functional indicator of risk in patients with coronary artery disease -- 4. The diagnostic and prognostic value of exercise ECG and radionuclide markers of ischemia in asymptomatic and symptomatic populations -- 5. An integrated clinical classification for ischemic heart disease: A combined assessment of severity of coronary disease, left ventricular function and myocardial ischemia -- Panel Discussion -- II Detection and Prognosis -- 6. Methods to detect ischemia using ambulatory (Holter) electrocardiography -- 7. The prognostic significance of silent myocardial ischemia during exercise testing -- 8. The role of radionuclide techniques in the evaluation of patients with silent myocardial ischemia -- Panel Discussion -- 9. Longitudinal (natural history) studies of silent myocardial ischemia -- 10. Silent myocardial ischemia and sudden cardiac death -- Panel Discussion -- IV Therapy and FDA Claims -- 11. Antianginal drug therapy for silent myocardial ischemia: Adrenergic blockers and calcium entry blockers -- 12. Therapy for silent ischemia: Nitrates -- 13. What are the FDA requirements to obtain a claim for the indication of silent ischemia? -- Panel Discussion -- V Combination Drug TherapyโFDA Issues -- 14. Combination drug therapy: What studies are required to obtain approval? -- Participant List