Title | Heart Hypertrophy and Failure [electronic resource] / edited by Naranjan S. Dhalla, Grant N. Pierce, Vincenzo Panagia, Robert E. Beamish |
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Imprint | Boston, MA : Springer US, 1995 |
Connect to | http://dx.doi.org/10.1007/978-1-4613-1237-6 |
Descript | XLII, 532 p. online resource |
A. Genetic and Molecular Events -- 1. Molecular analysis of genotype/phenotype correlations of hypertrophic cardiomyopathy -- 2. Molecular genetics: New mutations that cause familial hypertrophic cardiomyopathy -- 3. Genetically determined cardiomyopathies in neuromuscular disease -- 4. Mitochondrial DNA mutations and heart failure -- 5. Mutations of myocardial mitochondrial DNA in diabetic patients -- 6. Differential screening and megasequencing of human heart cDNA library: A search for genes associated with heart failure -- 7. Intracellular signaling and genetic reprogramming during development of hypertrophy in cultured cardiomyocytes -- 8. Phenotypic changes in experimental cardiac hypertrophy and failure in relation to changes in heart rate variability -- 9. Relationship between myocardial function and expression of calcium cycling proteins in nonfailing and failing human myocardium -- 10. Cardiac remodeling by alterations in phospholamban protein levels -- 11. Regulation of sarcoplasmic reticulum gene expression during cardiac hypertrophy and heart failure -- 12. Hormonal regulation of cardiac sarcoplasmic reticulum Ca2+-ATPase expression -- B. Cellular and Biochemical Mechanisms -- 13. Growth of the neonatal pig heart -- 14. Regulation of cardiac myocyte differentiation, hyperplasia, and hypertrophy during normal and stressed fetal and neonatal growth -- 15. Rat heterotopic cardiac isograft model: What atrophy teaches us about hypertrophy -- 16. Myocardial cell abnormalities in heart failure: Experience from studies on single myocytes -- 17. Depression of sarcolemmal phospholipase C activity in congestive heart failure -- 18 Does decreased energy supply contribute to heart failure? The role of the creatine kinase system -- 19 Molecular basis for depressed contractile performance in human heart failure -- 20 Cellular adaptations in hypertrophy and heart failure -- 21 Progressive ventricular dilatation in heart failure: The role of myocardial collagenase -- 22 Interaction between cardiac myocytes and the extracellular matrix in failing human myocardium -- 23 Role of transforming growth factor beta1 in the remodeling of collagen matrix in the heart -- 24 Cytokines modulate the expression of specific proteins of the contractile apparatus in rat myocytes -- C. Signal Transduction Abnormalities -- 25 Rethinking ras: p21 ras proteins and cardiac signal transduction -- 26 Regulation of ?MHC gene expression by cAMP -- 27 Cardiac hypertrophy and the renin-angiotensin system -- 28 Stimulation of ?-adrenoceptor subtypes causes different effects in cardiac cells -- 29 Significance of adrenergic stimuli for cardiac remodeling under chronic overload: Relative importance of myocardial factors versus ventricular geometry in cardiac failure -- 30 Sympathetic neuroeffector mechanisms in the failing and hypertrophied myocardium -- 31. Status of post adrenergic receptor mechanisms in cardiac hypertrophy and heart failure -- 32. Role of protein kinase C in the development of non-insulin-dependent diabetic cardiomyopathy -- 33. The alteration of signal transduction system in heart failure: renin-angiotensin system in diseased human heart -- 34. Neuroendocrine mechanisms in the pathogenesis of heart failure -- 35. Neurohormonal responses in congestive heart failure: effect of ACE inhibitors in randomized controlled clinical trials