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TitleMicrosurgery for Cerebral Ischemia [electronic resource] / edited by S. J. Peerless, C. W. McCormick
ImprintNew York, NY : Springer New York, 1980
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Descript XVIII, 372 p. online resource


In June 1973, Professor George Austin invited a small group of neuroscientists from Asia, Europe, the United States, and Canada to the Loma Linda University School of Medicine in Loma Linda, California. The fundamental technique of fashioning a small vessel collateral to the brain had been pioneered by Donaghy and Yasargil 5 years before and was now gaining momentum with the increased availability of the operating microscope, fine instruments and sutures, and surgeons trained in microvascular surgery. The interchange of ideas at this first conference was magic. The handful of participants returned home stimulated with new ideas of technique, patient selection, and postoperative evaluation and resolved to meet again on a regular basis. A Second International Symposium was hosted by Howard Reichman at Loyola University in Chicago, Illinois in June of 1974; a Third Symposium at Rottach-Egern, West Germany in June of 1976 under Professor F. Marguth of the Ludwig-Maximilians-University of Munich


I. Lectures by Dr. M.E. Raichle (Honored Guest of Symposium) -- 1. Role of erythrocyte carbonic anhydrase in oxygen delivery to brain. -- 2. Recent developments in the measurement of cerebral hemodynamics and metabolism. -- II. Cerebral Ischemia and Infarction -- 3. Serum and CSF brain-specific isoenzyme profiles in experimental cerebral ischemia and infarction. -- 4. Free radicals and oxygen during reperfusion. -- 5. A new model for chronic reversible cerebral ischemia. -- 6. Brain energetics in patients undergoing STA-MCA anastomosis. -- III. Cerebral Blood Flow -- 7. Changes in cerebral autoregulation in patients undergoing microanastomosis. -- 8. Regional cortical blood flow during cerebrovascular surgery. -- 9. The use of STA-MCA bypass in the evaluation of rCBF. -- 10. rCBF measurement in patients with STA-MCA shunts. -- 11. Cerebral blood flow in superficial temporal artery to middle cerebral artery anastomosis. -- 12. Experimental cerebral revascularization studied by 85Kr clearance and fluorescein angiography after 24 hours of permanent occlusion of the middle cerebral artery in dogs. -- 13. Regional cerebral perfusion assessed with 81mKr and emission computerized tomography. -- 14. The value of noninvasive regional CBF measurements in diagnostic and follow-up studies in cerebral vascular diseases with special regard to EIAB. -- IV. Noninvasive Methods of Investigation and EEG Analysis -- 15. Noninvasive management of stroke patients by Doppler sonography and dynamic radionuclide brain scanning. -- 16. Noninvasive evaluation of superficial temporal to middle cerebral artery anastomosis. -- 17. Intraoperative hemodynamic study by Doppler ultrasonic flowmeter in the extracranial-intracranial arterial bypass. -- 18. Ocular pneumoplethysmography in carotid occlusive disease. -- 19. Changes in collateral circulation and EEG analysis following extra-intracranial anastomosis. -- 20. The emergency STA-MCA bypass evaluated by the induced-functional EEG analysis in acute ischemic stroke. -- V. Radiology -- 21. Correlation of noninvasive Doppler and angiographic evaluation of extra-intracranial anastomoses. -- 22. STA-MCA anastomosis: Detailed analysis of pre- and postoperative angiography. -- 23. Angiography of the external carotid-internal carotid anastomosis (EC-IC). -- 24. Cortical artery pressure: Preoperative and postoperative arteriographic findings in patients with internal carotid artery occlusion. -- 25. Angiographic findings and cross-sectional brain perfusion studies after extra- intracranial arterial bypass. -- 26. Morphologic and functional correlates in transient cerebral ischemia. -- VI. Technical Aspects -- 27. In-situ dissections of brain with emphasis on blood supply at the base of the brain. -- 28. Successful adhesive repair of middle cerebral arteriotomy in primates. -- 29. A new technique for the end-to-side anastomosis between small arteries. -- 30. Safe microclip occlusive force for temporary vascular occlusion. -- 31. The influence of adventitial tissue to healing processes following microsurgical interventions on small vessels. -- 32. Ultrastructural control of small vessels following microsurgical intervention by tissue adhesion with fibrin. -- 33. Comparative evaluation of microvascular arterial graft: Arterial autograft versus human umbilical artery graft. -- 34. Patency, blood flow and histologic response in 2- to 3-mm arterial autografts. -- 35. Arterial dilatation and augmentation of blood flow in experimental arteriovenous fistulas. -- 36. The effect of heparin on the patency rate of autogenous vein grafts inserted into the arterial system of rats. -- 37. The quantitative assessment of the effect of antiplatelet drugs on thrombosis in microvascular anastomoses. -- 38. Relationship of internal carotid artery stump pressure to STA-MCA bypass function. -- 39. Measurement of intracranial arterial pressure in patients undergoing extracranial to intracranial microsurgical anastomosis for cerebrovascular ischemia. -- VII. Clinical Aspects -- 40. High cervical carotidopathies. -- 41. Extra-intracranial arterial bypass surgery for cerebral ischemia in patients with normal cerebral angiograms. -- 42. Revascularization in the acute stage of the MCA occlusion. -- 43. Cerebral microvascular surgery in completed stroke. -- 44. Extra-intracranial anastomosis operation associated with hyperbaric oxygenation in the treatment of completed stroke. -- 45. Extra-intracranial arterial bypass surgery in patients with bilateral internal carotid artery occlusions. -- 46. The surgical management of bilateral carotid artery occlusive disease. -- 47. Indications for surgery in patients with several cerebrovascular lesions. -- 48. Further experience with occipital artery-caudal loop-PICA anastomosis for vertebrobasilar insufficiency. -- 49. New approaches in cerebral revascularization. -- 50. Failure of EC-IC bypass to alter ischemia. -- 51. Hemorrhagic infarction after microsurgical cerebral revascularization. -- 52. Extracranial-intracranial anastomosis in cerebrovascular disease. -- 53. Results in 51 patients with EC-IC bypass: Technical and clinical considerations. -- 54. Microneurosurgical arterial bypass for cerebral ischemia: The San Francisco experience. -- 55. STA-MCA anastomosis: further analysis of long-term resultsโ{128}{148}A neurologistโ{128}{153}s view

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