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TitleAlzheimer Disease [electronic resource] : From Molecular Biology to Theraphy / edited by Robert E. Becker, Ezio Giacobini, Joyce M. Barton, Mona Brown
ImprintBoston, MA : Birkhรคuser Boston, 1997
Connect tohttp://dx.doi.org/10.1007/978-1-4612-4116-4
Descript XIV, 614 p. online resource

CONTENT

I. Pathological Basis of Therapy in Alzheimerโ{128}{153}s Disease -- Criteria for the Diagnosis of Alzheimerโ{128}{153}s Disease -- Neuropathology Of Alzheimerโ{128}{153}s Disease -- Processing of Amyloid, Cytoskeletal Damage and Apolipoproteins -- Cell Death: Excitotoxins, Apoptosis And Hypometabolism -- Neurotrophins, Growth Factors and Neuroprotectors -- Animal Models -- II. The Cholinergic System in Brain -- Treatment of Alzheimer Disease -- Cholinesterase Inhibitors in Alzheimer Disease Treatment -- III. Nicotinic and Muscarinic Cholinergic Agonists -- Nicotinic Agonists -- Muscarinic Agonists and Antagonists -- The Potential of Antioxidant Therapy -- The Potential for Anti-Inflammatory Therapy -- IV. Development of New Therapies in Alzheimer Disease -- Design of Clinical Trials -- Advances in Assessment -- SPECT and PET -- Potential Markers of Disease Progression and Drug Efficacy in Alzheimerโ{128}{153}s Disease -- Treatment of Behavioral and Psychosocial Disturbances -- V. Social Issue in Alzheimer Disease -- Legal and Ethical Issues -- Socio-Economic As pects of Alzheimer Disease Treatment -- International Harmonization of Drug Guidelines -- Research Priorities in Alzheimer Disease Treatment โ{128}{148} An International Perspective -- Author Index


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