Title | Bovine Spongiform Encephalopathy [electronic resource] : The BSE Dilemma / edited by Clarence J. Gibbs |
---|---|
Imprint | New York, NY : Springer New York, 1996 |
Connect to | http://dx.doi.org/10.1007/978-1-4612-2406-8 |
Descript | XXV, 413 p. online resource |
1. The Potential Risk to Humans of Amyloids in Animals -- I. Host Range and Pathogenesis -- 2. Bovine Spongiform Encephalopathy Distribution and Update on Some Transmission and Decontamination Studies -- 3. Preliminary Observations on the Pathogenesis of Experimental Bovine Spongiform Encephalopathy -- 4. Recent Observations on the Epidemiology of Bovine Spongiform Encephalopathy -- II. Transmission and Pathogenesis of Spongiform Encephalopathies -- 5. Scrapie: Studies on Vertical and Horizontal Transmission -- 6. Transmission of Sheep and Goat Strains of Scrapie from Experimentally Infected Cattle to Hamsters and Mice -- 7. Experimental Transmission of Scrapie to Cattle -- 8. An Assessment of Transmissible Mink Encephalopathy as an Indicator of Bovine Scrapie in U.S. Cattle -- 9. Experimental Infections of Cattle and Mink with the Agents of Transmissible Mink Encephalopathy, Scrapie, and Bovine Spongiform Encephalopathy -- 10. BSE-Free Status: What Does It Mean? -- 11. Differing Neurohistologic Images of Scrapie, Transmissible Mink Encephalopathy, and Chronic Wasting Disease of Mule Deer and Elk -- 12. Analysis of Risk Factors and Active Surveillance for BSE in Argentina -- 13. Speculations on the Origin of BSE and the Epidemiology of CJD -- III. Biochemistry: Protein Chemistry, Molecular Biology, and Molecular Genetics of the Spongiform Encephalopathies -- 14. Structure and Biologic Characteristics of Prion Protein (Scrapie Amyloid): Implications for the Safety of Naturally Derived Biologics -- 15. Prion Strains and Neuromuscular Disease in PrP Transgenic Mice -- 16. Deciphering Prion Diseases with Transgenic Mice -- 17. Posttranslational Modifications and Conformational Changes of PrPSc and Their Relationship to Infectivity -- 18. Amyloidosis: The Key to the Epidemiology and Pathogenesis of Transmissible Spongiform Encephalopathies -- 19. Effect of Amphotericin B on Different Experimental Strains of Spongiform Encephalopathy Agents -- IV. Pathogenesis, Molecular Biology and Genetics, and Immunohistochemistry -- 20. Genetics of Human Spongiform Encephalopathies: Current Status -- 21. PrP Allelic Variants Associated with Natural Scrapie -- 22. The Formation of Scrapie-Associated Prion Protein In Vitro -- 23. Proteinase K-Resistant Prion Protein Detection in Animal Tissues and In Vitro -- 24. Elimination of Scrapie-Agent Infectivity in Naturally Derived Biologics -- 25. Cellular and Scrapie Prion Protein Immunolocalization and In Vitro Amyloid Formation -- V. Public Health Considerations of Human and Animal Spongiform Encephalopathies -- 26. Real and Theoretical Threats to Human Health Posed by the Epidemic of Bovine Spongiform Encephalopathy -- 27. Incidence of Creutzfeldt-Jakob Disease in the European Community -- 28. Problems in the Evaluation of Theoretical Risks for Humans to Become Infected with BSE-Contaminated Bovine-Derived Pharmaceutical Products -- 29. Evaluation of BSE Risk Factors Among European Countries -- Author Index