Title | Growth Hormone Secretagogues [electronic resource] / edited by Barry B. Bercu, Richard F. Walker |
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Imprint | New York, NY : Springer New York, 1996 |
Connect to | http://dx.doi.org/10.1007/978-1-4612-2396-2 |
Descript | XXII, 460p. 117 illus. online resource |
I. Overview: Historical Perspective -- Growth Hormone Releasing Factor: A Brief History of Its Time -- 2. Xenobiotic Growth Hormone Secretagogues: Growth Hormone Releasing Peptides -- II. Chemistry of Growth Hormone Secretagogues -- 3. Synthetic Analogues of Growth Hormone Releasing Factor (GHRF) with Improved Pharmaceutical Properties -- 4. Structure, Function, and Regulation of the Pituitary Receptor for Growth Hormone Releasing Hormone -- 5. Computer-Assisted Modeling of Xenobiotic Growth Hormone Secretagogues -- 6. Growth Hormone Releasing Peptides -- 7. Nonpeptidyl Growth Hormone Secretagogues -- 8. A Weak Substance P Antagonist Inhibits L-692,585-Stimulated GH Release in Swine -- 9. Growth Hormone Releasing Hormone Receptor in Human Breast Cancer Cell Line MCF-7 -- III. Cellular and Molecular Properties of Growth Hormone Secretagogues -- 10. Cellular Physiology of Growth Hormone Releasing Hormone -- 11. Mechanism of Action of GHRP-6 and Nonpeptidyl Growth Hormone Secretagogues -- 12. Metabolic Regulation of Growth Hormone Secretagogue Gene Expression -- IV. Physiology of Growth Hormone Secretagogues -- 13. The Role of Growth Hormone Releasing Hormone (GHRH) and Growth Hormone (GH) in the Onset of Puberty and During Glucocorticoid-Altered Growth -- 14. Clinical Studies with Growth Hormone Releasing Hormone -- 15. Central and Peripheral Effects of Peptide and Nonpeptide GH Secretagogues on GH Release In Vivo -- 16. Evidence for a Central Site and Mechanism of Action of Growth Hormone Releasing Peptide (GHRP-6) -- 17. Animal Models for Evaluating Xenobiotic Growth Hormone Secretagogue Activity -- 18. A Diagnostic Test Employing Growth Hormone Secretagogues for Evaluating Pituitary Function in the Elderly -- V. Target Tissues and Applications for Growth Hormone Secretagogues -- 19. Transdifferentiation of Growth Hormone and Prolactin Secreting Cells -- 20. Growth Hormone Releasing Hormone: Behavioral Evidence for Direct Central Actions -- 21. Growth Hormone (GH) Releasing Hormone- and Thyrotropin Releasing Hormone-Induced GH Release in the Acute Phase of Trauma -- 22. Effects of Hexarelin on Growth Hormone Secretion in Short Normal Children, in Obese Children, and in Subjects with Growth Hormone Deficiency -- 23. Lymphocytes and Hypothalamic Peptides -- 24. Growth Hormone Releasing PeptideโHexarelinโin Children: Biochemical and Growth Promoting Effects -- 25. Growth Hormone Secretagogues in Disease States Associated with Altered Growth Hormone Secretion -- 26. Growth Hormone Releasing Hormone (GHRH) Effects in Healthy Aging Men -- 27. Aging and Growth Hormone Releasing Peptides -- 28. Growth Hormone Relationships to Immune Function in Humans -- Author Index