Title | Cell Death and Diseases of the Nervous System [electronic resource] / edited by Vassilis E. Koliatsos, Rajiv R. Ratan |
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Imprint | Totowa, NJ : Humana Press : Imprint: Humana Press, 1999 |
Connect to | http://dx.doi.org/10.1007/978-1-4612-1602-5 |
Descript | XXI, 683 p. online resource |
I. DefinitionsโCellular and Molecular Mechanisms -- 1. Apoptosis Versus Necrosis: How Valid a Dichotomy for Neurons? -- 2. Asynchronous Death as a Characteristic Feature of Apoptosis -- 3. Free Radicals and Mitochondria Dysfunction in Excitotoxicity and Neurodegenerative Disease -- 4. Calcium and Cell Death -- 5. Proteases: Critical Mediators of Apoptosis -- 6. The Cell Cycle and Neuronal Cell Death -- II. Animal Models -- 7. Neuronal Cell Death in C. elegans -- 8. Cellular Interactions that Regulate Programmed Cell Death in the Developing Vertebrate Nervous System -- 9. Axotomy-Induced Motor Neuron Death -- 10. Excitotoxic Cell Death -- 11. Neurotoxins and Neuronal Death:An Animal Model of Excitotoxicity -- III. Nerve Cell Death in Human Diseases -- 12. DNA Repair and Neurological Diseases -- 13. Cell Death and the Mitochondrial Encephalomyopathies -- 14. Viral Encephalitis -- 15. Mechanisms of Cell Injury in Prion Diseases -- 16. Blood Flow, Energy Failure, and Vulnerability to Stroke -- 17. Epilepsy and Cell Death -- 18. Trauma to the Nervous System -- 19. Approaches to the Study of Diseases Involving Oligodendroglial Death -- 20. Motor Neuron Disease -- 21. Cerebellar Degenerations -- 22. Parkinsonโs Disease -- 23. Huntingtonโs Disease and DRPLA: Two Glutamine Repeat Diseases -- 24. Cortical Destruction and Cell Death in Alzheimerโs Disease -- 25. HIV-1 Infection of the CNS: Evidence for Apoptosis of Nerve Cells -- 26. Neurotoxicity of Drugs of Abuse -- 27. Schizophrenia -- IV. Approaches in Treating Nerve Cell Death -- 28. Trophic Factors as Therapeutic Agents for Diseases Characterized by Neuronal Death -- 29. Early Experiences with Trophic Factors as Drugs for Neurological Disease: Brain-Derived Neurotrophic Factor and Ciliary Neurotrophic Factor for ALS -- 30. Approaches in Treating Nerve Cell Death with Calcium Chelators -- 31. Antiglutamate Therapies for Neurodegenerative Disease: The Case of Amyotrophic Lateral Sclerosis -- 32. Antioxidants and the Treatment of Neurological Disease