Title | GHRH, GH, and IGF-I [electronic resource] : Basic and Clinical Advances / edited by Marc R. Blackman, Jesse Roth, S. Mitchell Harman, Jay R. Shapiro |
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Imprint | New York, NY : Springer New York : Imprint: Springer, 1995 |
Connect to | http://dx.doi.org/10.1007/978-1-4612-0807-5 |
Descript | XIX, 319 p. online resource |
I. Overview of Physiology of the GHRH-Somatostatin-GH-IGF-I Axis -- 1. Physiology of the Growth Hormone Releasing Hormone-Somatostatin-Growth Hormone-Insulin-Like Growth Factor I Axis -- 2. Role of Somatostatin in the Regulation of Growth Hormone Secretion -- 3. Growth Hormone Releasing Hormone and Growth Hormone Releasing Peptides -- 4. GH Binding Protein, GH Receptors, and Domains Involved in Signal Transduction -- 5. Insulin-Like Growth Factors During Development -- II. Effects of Recombinant Human GH and/or IGF-I in Catabolic Illness -- 6. Anabolic Effects of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Human Disease -- 7. Growth Hormone in Children with Chronic Renal Disease: Some Metabolic Considerations -- 8. Growth Hormone: The Visible Difference in Burn Care -- 9. Effects of Recombinant Human Growth Hormone on Body Composition and Metabolism in HIV-Associated Wasting -- 10. Administration of Growth Hormone as an Adjunct to Nutritional Support in Critical Illness -- 11. Strategies for the Use of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Amyotrophic Lateral Sclerosis -- III. Contemporary Issues in Growth and Development -- 12. Contemporary Issues in Growth and Development: An Overview -- 13. Use of Recombinant IGF-I in Syndromes of GH Insensitivity -- 14. Use of Growth Hormone in Non-Growth-Hormone-Deficient Children: Physiologic, Pharmacologic, and Ethical Issues -- 15. Growth Hormone Treatment of Nonelderly Adults with GH Deficiency -- IV. Effects of rhGH and IGF-I on Intermediary and Bone Metabolism -- 16. Overview of Growth Hormone and IGF-I Effects on Intermediary Metabolism and Bone -- 17. Effects of rhGH on Glucose, Lipid, and Amino Acid Metabolism -- 18. Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus -- 19. Modulation of Responses to GH and IGF-I by Nutritional Variables -- 20. Growth Hormone Effects on the Adult Skeleton -- 21. Insulin-Like Growth Factors and Skeletal Remodeling -- V. Use of GHRH, rhGH, and rhIGF-I in Aging -- 22. Growth Hormone and Aging: A Brief Review -- 23. Potential Benefits and Risks in Treating the Hyposomatomedinemia and Hypogonadism of Elderly Men -- 24. Effects of Growth Hormone Releasing Hormone Administration in Healthy Aging Men -- 25. Effects of Recombinant Human Insulin-Like Growth Factor I in Aging -- 26. Growth Hormone and Immune Function in the Elderly -- 27. Treatment with Growth Hormone: Focus on Specificity with a View to the Future -- Author Index