Title	Motor Neuron Disease [electronic resource] : Biology and Management / edited by P. N. Leigh, Michael Swash
Imprint	London : Springer London, 1995
Connect to	http://dx.doi.org/10.1007/978-1-4471-1871-8
Descript	XVIII, 468p. 86 illus. online resource

Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND

Contents: Motor Neuron Disease: The Clinical Syndrome. Epidemiology of Motor Neuron Disease -- Familial Motor Neuron Disease -- Pathology of Motor System Disorder. The Pathology of Motor Neuron Disease. Alternative Approaches to the Pathology of Motor Neuron Disease. The Molecular Pathology of Motor Neuron Disease. Neurochemistry of Motor Neuron Disease -- Calcium and Aluminium in the Chamorro Diet: Unlikely Causes of Alzheimer-Type Neurofibrillary Degeneration on Guam -- Toxicology of Motor Systems -- Theories of Causation -- Somatic Motoneurons and Descending Motor Pathways. Limbic and Non-limbic Components -- Neurophysiological Changes in Motor Neuron Disease -- Clinical Pharmacology of Motor Neurons -- The Management of Motor Neuron Disease -- Clinical Trial Methodology -- New Therapeutic Approaches: Rationale and Results. Living with Motor Neuron Disease