Author | Weller, Roy O. author |
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Title | Clinical Neuropathology [electronic resource] / by Roy O. Weller, Michael Swash, D. Lindsay McLellan, Carl L. Scholtz |
Imprint | London : Springer London, 1983 |
Connect to | http://dx.doi.org/10.1007/978-1-4471-1335-5 |
Descript | XVII, 329 p. online resource |
1. Development of Neurology and Neuropathology -- Early concepts of neurological structure and function -- 2. Functional Histology and Anatomy of the Central Nervous System -- Histology of the brain -- Anatomy of the human brain -- Anatomy of the spinal cord -- Basic neuroanatomy from the study of brain evolution -- Further reading -- 3. The Interpretation of Neurological Symptoms and Signs -- Clinical localisation of brain disorders -- Interaction between focal and generalised effects of intracranial lesions -- Spinal cord lesions -- Peripheral nerve disease -- Conclusion -- Further reading -- 4. General Pathology of the Central Nervous System -- Reactions of brain cells to disease processes -- Reactions to brain tissue damage -- The secondary effects of intracranial space-occupying lesions and cerebral oedema -- Hydrocephalus -- Further reading -- 5. Cerebral Vascular Disease -- Stroke -- Physiological aspects of the cerebral circulation -- Cerebral infarcts -- Hypoxic encephalopathy -- Spinal cord infarction -- Venous infarction -- Intracranial haemorrhage -- Further reading -- 6. Trauma to the Nervous System -- Head injuries -- Spinal cord trauma -- Chronic and recurrent trauma to the nervous system -- Radiation myelopathy and encephalopathy -- Further reading -- 7. Intracranial and Spinal Tumours -- Classification -- Incidence of intracranial and spinal tumours -- Clinical presentation of intracranial tumours -- Diagnosis of intracranial tumours -- Intracranial tumours of neuro-epithelial origin -- Tumours of nerve sheath cells -- Meningiomas -- Primary malignant lymphomas of the brain -- Tumours and malformations of blood vessel origin -- Tumours of the pituitary -- Tumours of the pineal -- Metastatic intracranial tumours -- Spinal tumours -- Further reading -- 8. Pituitary Tumours -- Pituitary adenomas -- Craniopharyngiomas and suprasellar cysts -- Further reading -- 9. Virus Infections of the Nervous System -- Clinical aspects and pathology -- Virology of nervous system infections -- Virological investigations in CNS infections -- Investigation of encephalitis -- Further reading -- 10. Bacterial, Fungal and Parasitic Infections of the Central Nervous System -- Bacterial infections -- Bacterial meningitis -- Tuberculous meningitis and tuberculomas -- Neurosyphilis -- Shunt-associated meningitis -- Fungal meningitis -- Other causes of meningitis -- Intracranial abscess -- Mycotic aneurysms -- Protozoal infections -- Metazoal parasites -- Further reading -- 11. Developmental and Neonatal Neuropathology -- Epidemiology -- Pathogenetic considerations -- Development of the human brain -- Chromosomal abnormalities -- Destructive lesions -- Dysraphic malformations -- Hydrocephalus -- Syringomyelia -- Perinatal brain injuries -- The phakomatoses -- Pathology of metabolic disorders of the brain -- Pathology of inborn lysosomal storage disorders -- Further reading -- 12. Metabolic Disorders Affecting the Nervous System -- Neonatal hypothyroidism -- Phenylketonuria -- Disorders of the branched chain amino acids -- Disorders of sulphur metabolism -- Urea cycle disorders -- Carbohydrate disorders -- Inherited disorders of trace metal metabolism -- Diagnosis of inherited disorders of sick infants -- References -- 13. Inborn Lysosomal Storage Disorders Affecting the Nervous System -- Lysosomes and lysosomal storage disorders -- Lysosomal disorders affecting the nervous system -- The mucopolysaccharidoses -- The lipidoses -- The mucolipidoses -- Other lysosomal disorders affecting the nervous system -- Aids to diagnosis of lysosomal disorders -- Management of lysosomal disorders -- References -- 14. Hereditary and System Disorders of the Nervous System -- Clinical features -- Hereditary system degenerations -- Acquired system degenerations -- Further reading -- 15. Dementia -- Epidemiology -- Causes -- Alzheimerโs disease -- Multi-infarct dementia -- Pickโs disease -- Progressive subcortical gliosis -- Huntingtonโs disease -- Creutzfeldt-Jakob disease (subacute spongiform encephalopathy) -- The amnesic syndrome -- Intermittently raised pressure hydrocephalus (IRPH) -- Further reading -- 16. Diseases of Peripheral Nerve -- Nerve biopsy -- Autopsy study of peripheral neuropathies -- Techniques for peripheral nerve histology -- Anatomy of peripheral nerves -- Histology of peripheral nerves -- Development and ageing of peripheral nerves -- General pathology of peripheral nerves -- Axon (wallerian) degeneration and regeneration -- Peripheral nerve diseases -- Further reading -- 17. Diseases of Muscle -- Muscle biopsy technique -- Histological features of neuromuscular disease -- Classification of neuromuscular disorders -- Myopathic disorders -- End-plate disorders -- Inflammatory myopathies -- Neurogenic disorders -- Further reading