1. Introduction -- 2. Historical Aspects -- A. The Normal Adrenal Cortex -- 3. Origin and Development of the Adrenal Gland -- 4. Structure of the Adult Adrenal Cortex -- 5. The Effect of Stress on the Structure of the Adrenal Cortex -- 6. Morphological Changes in the Adrenal Cortex with Age -- 7. Iatrogenic Changes -- 8. Functional Activity of the Adrenal Cortex -- 9. Regulation of Growth of the Adrenal Cortex -- 10. Functional Zonation of the Adrenal Cortex -- B. Hypercorticalism -- 11. General Incidence and Pathological Changes -- 12. Cushing's Syndrome -- 13. The Adrenogenital Syndrome and Related Conditions -- 14. The Distinction Between Benign and Malignant Adrenocortical Tumours Causing Cushing's and/or the Adrenogenital Syndromes: Structural and Functional Criteria -- 15. Hyperaldosteronism and Related Syndromes of Mineralocorticoid Excess -- 16. โ{128}{152}Non-functioning' (Non-hormonal) Adrenocortical Tumours -- C. Hypocorticalism -- 17. Acute Acquired Adrenoprivic Hypocorticalism -- 18. Chronic Acquired Adrenoprivic Hypocorticalism (Addison's Disease) -- 19. Congenital Adrenoprivic Hypocorticalism -- 20. Tropoprivic Hypocorticalism -- D. Other Pathological Changes -- 21. Haemorrhage and Necrosis -- 22. Congenital Defects of Adrenal Development -- 23. Myelolipoma and Related Changes -- 24. Cysts -- 25. Miscellaneous Changes -- Appendix A. Plasma Steroids -- Appendix B. Urinary Steroids -- References