Office of Academic Resources
Chulalongkorn University
Chulalongkorn University

Home / Help

TitleCalcium Channel Pharmacology [electronic resource] / edited by Stefan I. McDonough
ImprintBoston, MA : Springer US : Imprint: Springer, 2004
Connect to
Descript XV, 418 p. online resource


Voltage-gated calcium channels are critical regulators of cytoplasmic levels of calcium, the universal signaling ion. As such, calcium channels trigger a wide range of cellular functions, from muscle contraction to neurotransmitter secretion, and are important players in human disease. Prominent in the nervous, cardiovascular, and endocrine systems, members of the calcium channel family are targets for existing antihypertensive and anticonvulsant drugs. In addition, they are emerging targets for drugs to treat an extraordinarily diverse group of disorders, including pain, cerebral ischemia, cardiac arrhythmia, and migraine. This book reviews the compounds that target individual calcium channel subtypes and the cellular and behavioral functions governed by each different channel. It contains information for basic scientists using calcium channel antagonists as experimental tools, for behavioralists studying animal models of human disease, and for pharmaceutical scientists interested in creating the next generation of calcium channel-targeted drugs. Several factors make an entire book on calcium channel pharmacology timely


Concepts of State-Dependent Pharmacology of Calcium Channels -- Pharmacology of Cav1 (L-Type) Channels -- The Therapeutic Utility of Targeting Cv2 Channels -- Peptide Toxin Inhibition of Voltage Gated Calcium Channels: Selectivity and Mechanisms -- Calcium Channel Blocking Polypeptides: Structure, Function, and Molecular Mimicry -- Pharmacology of Cav3 (T-Type) Channels -- Cellular Functions of Calcium Channel Subtypes -- Genetic Approaches to the Elucidation of Calcium Channel Functions in Vivo -- Calcium Channel Mutations and Associated Diseases -- Modulation of High Voltage-Activated Calcium Channels by G Protein- Coupled Receptors -- Alternative Splicing in Voltage GatedCalcium Channels

Medicine Neurosciences Cardiology Veterinary medicine Biochemistry Biophysics Biological physics Medicine & Public Health Veterinary Medicine Biophysics and Biological Physics Biochemistry general Neurosciences Cardiology


Office of Academic Resources, Chulalongkorn University, Phayathai Rd. Pathumwan Bangkok 10330 Thailand

Contact Us

Tel. 0-2218-2929,
0-2218-2927 (Library Service)
0-2218-2903 (Administrative Division)
Fax. 0-2215-3617, 0-2218-2907

Social Network


facebook   instragram