Normal Colon -- A. Anatomic Considerations -- B. Histology -- Pathology -- A. General Prevalence and Anatomic Distribution -- B. Gross Appearance -- C. Microscopic Features -- D. Differential Diagnosis -- E. The Diminutive Polyp -- F. Other Characteristics of Polyps -- G. Histogenesis of Polyps -- Adenomatous Polyposes -- A. Familial Polyposis Coli and Gardnerโ{128}{153}s Syndrome -- B. Other Adenomatous Polyposis Syndromes -- C. The Genetics of Adenoma Transmission -- Malignant Potential of Adenomatous Polyps -- A. Association of Polyps and Carcinomas -- B. Histological Evidence of Malignant Transformation -- C. Adenomatous Remnants in Carcinomas -- D. Epidemiological Evidence and Etiological Factors -- E. Findings in Experimental Animals -- F. Alternate Hypotheses of Carcinogenesis -- G. Conclusions -- Detection and Management -- A. Screening, Diagnostic, and Surveillance Techniques -- B. The Malignant Polyp -- C. Endoscopic Polypectomy -- D. Postpolypectomy Surveillance Recommendations -- E. The National Polyp Study -- F. Polyp Registries -- Conclusions -- Glossary and Abbreviations