1 Introduction Fetal/Perinatal imprinting on later life -- 2 Perinatal origins of adult disease Obesity -- 3 Perinatal origins of adult disease Insulin resistance and Diabetes mellitus -- 4 Perinatal origins ofadult disease Hypertension -- 5 Perinatal origins of adult disease Coronary heart disease -- 6 Metabolic Syndrome X and low-grade systemic inflammation -- 7 Long-chain polyunsaturated fatty acids in adult diseases: A hypothesis -- 8 Breast-feeding Composition and benefits -- 9 Long-chain polyunsaturated fatty acids Metabolism, physiology and clinical significance -- lO A perinatal strategy to prevent adult diseases: The Role of long-chain polyunsaturated fatty acids Clinical implications and testing the hypothesis