Title | Textbook of Coronary Thrombosis and Thrombolysis [electronic resource] / edited by Richard C. Becker |
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Imprint | Boston, MA : Springer US, 1997 |
Connect to | http://dx.doi.org/10.1007/b102433 |
Descript | XXI, 679 p. online resource |
Scientific Principles -- Biochemistry of Intra Vascular Clotting: Focus on the Prothrombinase Complex -- Plasma Coagulation Factors -- Platelets: Structure, Function, and Their Fundamental Contribution to Hemostasis and Pathologic Thrombosis -- Molecular Regulation of Fibrinolysis -- Plasminogen Activator Inhibitor-1 -- Biological Effects of Targeted Gene Inactivation and Gene Transfer of the Coagulation and Fibrinolytic Systems in Mice -- Molecular Approaches to The Design of New Thrombolytic Agents -- Endothelial Cell Biology -- Physiology of Vascular Homeostasis -- Coronary Vascular Pharmacology -- Experimental Models of Coronary Arterial Resistance and Blood Flow -- Pathogenesis of the Acute Coronary Syndromes: Hypotheses Generated from Clinical Experience -- Plaque Disruption and Thrombosis: Models to Evaluate Acute Cardiovascular Events -- Developing Antithrombotic and Thrombolytic Agents: The Role of Experimental Models -- Clinical Application of Scientific Principles -- Streptokinase: Biochemistry and Phamacokinetics -- Anistreplase (Anisoylated Plasminogen Streptokinase Activator Complex, Apsac) in Coronary Thrombolysis -- Biochemistry, Pharmacokinetics, and Dynamics of Single- and Two- Chain Urokinase -- Staphylokinase: Biochemistry And Pharmacodynamics -- Novel Tissue Plasminogen Activators: Reteplase (R-PA) -- Chemistry, Pharmacokinetics, and Pharmacodynamics of T-PA, TNK and DSPA Alpha 1 -- National Goals and Perspectives for Improving Patient Care: the National Heart Attack Alert Program -- Delays in Treatment of Acute Myocardial Infarction in the Emergency Department: Reducing Door to Drug Time -- Factors Associated With Prehospital Delay And Overview Of Community Trials To Reduce The Duration Of Prehospital Delay In Patients With Symptoms Of Acute Coronary Disease -- Emergency Medical Services -- Prehospital Approaches to Treating Sudden Cardiac Death and Acute Myocardial Infarction -- Identification of Acute Cardiac Ischemia in the Emergency Department -- The Scientific Basis and Rationale For Early Thrombolytic Therapy -- Patient Selection for Thrombolytic Therapy for Evolving Myocardial Infarction -- Aspirin, Heparin, and New Antithrombotic Drugs as Adjuncts to Thrombolytic Therapy for Acute Myocaradial Infarction -- New Antiplatelet Strategies in the Adjunctive Treatment of Acute Myocardial Infarction -- Experimental Evidence for Enhancement of Thrombolysis by Conventional Thrombolytic Drugs -- Early Diagnosis of Myocardial Infarction with MB-CK Subforms -- Troponins as early markers of acute myocardial infarction -- Markers of Thrombosis and Fibrinolysis -- Markers of Coronary Recanalization after Thrombolysis -- Anticoagulant Monitoring -- Anticoagulation Monitoring for Percutaneous Transluminal Coronary Angioplasty -- Monitoring Chronic Oral Anticoagulant Therapy -- Hemorrhagic Complications -- Gene therapy for the vulnerable plaque -- Gene Therapy: Vector Design and Current Challenges -- New Dimensions -- Role of Inflammation Following Myocardial Ischemia and Reperfusion -- Estrogen and Cardiovascular Disease -- Evolution of Thrombocardiology -- Drugs in Development -- Clinical Trials of Novel Antithrombotics: Basic Concepts of Study Design and Methodology -- A Glossary of Terms in Thrombocardiology