Title | Sucralfate [electronic resource] : From Basic Science to the Bedside / edited by Daniel Hollander, Guido N. J. Tytgat |
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Imprint | Boston, MA : Springer US, 1995 |
Connect to | http://dx.doi.org/10.1007/b102476 |
Descript | XXV, 366 p. 60 illus., 9 illus. in color. online resource |
Pathophysiology of Peptic Ulcer Disease -- Decreased Intragastric Acid Concentration as an Approach to Peptic Disease Therapy -- General Approach to Peptic Disease Therapy -- Ulcer Healing by Strengthening of Mucosal Defense -- History of the Development of Sucralfate -- Sucralfate: A Nonsystemic Site Protective Agent -- Chemistry of Sucralfate -- Binding of Bile Acids by Sucralfate -- Mechanisms of Action of Sucralfate -- Binding of Sucralfate to the Mucosal Surface -- Stimulation of Mucus Production -- Gastroduodenal Bicarbonate Secretion and its Response to Sucralfate -- Effect of Sucrose Octasulfate on Isolated Gastric Cells -- Effect on Gastric Surfactant -- Stimulation of Mucosal Prostaglandins by Sucralfate -- Sucralfate and Helicobacter pylori -- Sucralfate and Cell Proliferation -- Vascular Factors -- Sucralfate -- Effects of Sucralfate on Growth Factor Availability -- Duodenal Ulcer Therapy, โAcid Rebound,โ and Early Relapse -- Effect of Sucralfate on Experimental Ulcers -- Effect on Experimental Esophageal Injury -- Safety and Drug Interactions -- Safety of Sucralfate -- Sucralfate Drug Interaction Studies -- Sucralfate and Therapy of Peptic Disease -- Therapy of Gastric Ulcer Disease -- Therapy of Active Duodenal Ulcers -- Prevention of Ulcer Recurrence -- Therapy of Esophagitis -- Sucralfate for NSAID-Induced Gastroduodenal Lesions -- The Preventive Use of Sucralfate -- Sucralfate for Prevention of Acute Gastrointestinal Bleeding -- Prevention of Respiratory Tract Infections with Sucralfate in Ventilated ICU Patients -- Sucralfate in Nonulcer Dyspepsia, Gastritis, and Duodenitis -- Use of Sucralfate in Variceal Sclerotherapy-Induced Ulcerations -- The Clinical Role of Sucralfate in Peptic Ulcer TherapyโComparison with H-2 Blockers and Pump Inhibitors: A Projection for the Nineties -- Future Research into the Mechanisms of Action of Sucralfate -- Future Clinical Development of Sucralfate