Title | Insulin & Related Proteins - Structure to Function and Pharmacology [electronic resource] / edited by Markus Leyck Dieken, Matthias Federwisch, Pierre De Meyts |
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Imprint | Dordrecht : Springer Netherlands, 2002 |
Connect to | http://dx.doi.org/10.1007/0-306-47582-0 |
Descript | XIV, 252 p. online resource |
How Insulin Came from Heidelberg to Aachen and Why it Took Five Years -- Insulin at the German Wool Research Institute-Retrospect and Outlook -- Insulin: Sequence, Structure and Function - A Story of Surprises -- The Association/Dissociation Equilibria of Insulin in the Presence of Metal Ions: A Fluorescence Energy Transfer and Circular Dichroism Study -- Self-Association of Insulin Reconsidered -- Self-Association of Insulin Reconsidered -- T-R Transition -- Comparison of Conformational Transitions in Proteins -- Activities of Insulin Analogues at Position A8 are Uncorrelated with Thermodynamic Stability -- Relationships between the Structure of Insulin and its Physiological Effects -- Structure-Function Relationships of Insulin and Insulin-Like Growth factor-I Receptor Binding -- Structural Relationships between Members of the Insulin Receptor Family -- Insulin Interaction with Minimized Receptors and Binding Proteins -- Identification of Susceptibility Loci for Obesity, Insulin Resistance, and Hyperglycemia in a Backcross Model of New Zealand Obese (NZO) and Lean SJL Mice -- Activation Mechanism of Fibroblast Growth Factor Receptor Tyrosine Kinase Revealed by Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Fibroblast Growth Factor and Heparin -- IL-6 Type Cytokine Receptor Complexes -- Inhibition of Growth Factor Stimulated Pathways for the Treatment of Prostate Cancer -- Molecular Dynamics Simulations of Carbonmonoxy Myoglobin and Calculations of Heme Circular Dichroism