Title | Systems Theory in Immunology [electronic resource] : Proceedings of the Working Conference, Held in Rome, May 1978 / edited by Carlo Bruni, Gino Doria, Giorgio Koch, Roberto Strom |
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Imprint | Berlin, Heidelberg : Springer Berlin Heidelberg, 1979 |
Connect to | http://dx.doi.org/10.1007/978-3-642-93130-7 |
Descript | XI, 277 p. online resource |
I. Antigenic Stimulation -- Mechanism of B Lymphocyte Activation -- Clonal Dominance: Presentation of Antigenic Subsites is the Determining Factor -- Hierarchic Immunogenicity of Protein Determinants -- Control of B Lymphocyte Activation through Reversible Binding of Multivalent Antigen: a Simple Model -- II. Cell Interactions -- Some Cellular Interactions Involved in the Primary Immune Response -- Some Models for the Interaction between Cells of the Immune Systems -- Stimulation of Memory Cells and Abrogation of Suppression with a Mobile Antigen โ laden Cell -- Involvement of the Fc Receptor in Immune Regulation: a Hypothesis -- III. Evaluation and Evolution of Antibody Production -- Problems in the Evaluation of Antibody Affinity Distribution during the Immune Response -- Biological Variations of IgM Antibody Affinity -- Speculations on some Fundamental Aspects of the Regulation of the Quantity and Affinity of Antibody Produced during an Immune Response -- IV. Mathematical Modeling in Immunology -- Deterministic and Stochastic Bounded Rate Models in Immunology -- Some Basic Properties of Stochastic Population Models -- Systems Compartmentation in Immunological Modeling -- A Mathematical Model of the โTwo Signalโ Theory for T-B Cells Cooperation -- V. The Network Approach -- Idiotypic Regulation and H2 Restriction -- Immunoglobulin Gene Suppression and Expression -- Complexity and Regulation of the Immune System: the Network Approach -- The Stability of the Immune Network -- A Mathematical Model of the Stable States of a Network Theory of Self-Regulation -- Approaches for Data Reduction in Biological Networks