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AuthorBaranov, Alexander. author
TitleClinical Pre Computer Proforma for the International Computer Database for Radiation Exposure Case Histories [electronic resource]
ImprintBerlin, Heidelberg : Springer Berlin Heidelberg, 1994
Connect tohttp://dx.doi.org/10.1007/978-3-642-78740-9
Descript XIV, 114p. 2 illus. online resource

SUMMARY

This publication provides guidance on preparing data to be input into an international computerised database for clinical case histories of persons accidentally exposed to whole body irradiation. The publication has resulted from a close collaboration between the Institute of Biophysics including its Hospital Number 6 in Moscow, Russia, and the Institute of Occupational and Social Medicine at the University of Ulm. In both institutions, much experience has been accumulated during the last 20 years in dealing with basic and clinical research in the field of radiation accident management. In both institutions many case histories of radiation accident victims have been recorded. On this basis the scientists and clinicians from both institutions developed, over the last two years, a pre computer proforma to feed the International Computer Database for Radiation Exposure Case Histories, with standardised data from clinical case histories of radiation accident victims. This activity should be seen as part of WHO efforts to establish a network of institutions around the world, competent in Radiation Emergency Medical Preparedness and Assistance. This network has become known as REMPAN and it is prepared to provide medical advice and assistance when a radiation accident occurs in any country. The Institute of Occupational and Social Medicine, at the University of Ulm, is part of this global network


CONTENT

1. General Data on the Irradiated Patient -- 1.1 Demographic Data -- 1.2 Occupation at the Time of the Accident -- 1.3 History at the Time of the Accident -- 1.4 Institutions Involved in Patient Care and Database Recording -- 2. Accident Information and Personal Exposure Conditions -- 2.1 Accident Description -- 2.2 Source of Irradiation -- 2.3 Personal Exposure Conditions -- 3 Clinical Data After Exposure -- 3.1 Primary Reaction -- 3.2 Involvement of the Nervous System and the Eyes -- 3.3 Radiation Induced Lesions of Skin, its Appendices, and Underlying Tissues -- 3.4 Bone Marrow Syndrome and Blood -- 3.5 Radiation Induced Lesions of Gastrointestinal Tract -- 3.6 Organs Especially Sensitive Under Certain Exposure Conditions -- 3.7 Lesions of Other Organs -- 4. Treatment and Drugs -- 4.1 Individual Radiation Protection Measures -- 4.2 Physical Methods of Treatment -- 4.3 Substituting Therapy by Blood and Blood Products -- 4.4 Drugs -- 4.5 Haemostimulators -- 4.6 Haemopoietic Stem Cell Transplantation -- 5. Clinical Status at the Time of Reporting -- 5.1 Survival Status -- 5.2 Clinical Status -- 5.3 Functional Status -- 6. Skin Burns -- 6.1 Burn Score -- 6.2 Localisation Coding - Total Body, Head, Neck and Upper Trunk -- 6.3 Localisation Coding - Arms, Lower Trunk -- 6.4 Localisation Coding - Lower Trunk, Legs -- 6.5 Skin Burns -- 7. Haematopoietic Stem Cell Transplantation -- 7.1 Source of Stem Cells -- 7.2 Type of Transplantation -- 7.3 Histocompatibility Tests for Allogeneic Transplantation -- 7.4 Donor Information -- 7.5 Transplant Manoeuvre -- 7.6 Drugs to Prevent Acute Graft-versus-Host Disease (GvHD) -- 7.7 In vitro and in vivo Removal of Donor T Cells to Prevent GvHD -- 7.8 Evidence for Haemopoietic Engraftment -- 7.9 Overall Evaluation of Engraftment -- 7.10 Graft-versus-Host Disease -- 7.11 Specific Therapy for GvHD -- 8. Annexes -- 8.1 IAEA International nuclear event scale -- 8.2 Conversion of Non-SI to SI Units -- 8.3 Orders of Magnitude -- 8.4 Karnofsky Scale for Rating Activity Status -- 8.5 References -- 8.6 Normal Values of Laboratory Parameters -- 8.7 Pages for copying


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