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TitleSystematic reviews in pain research : methodology refined / editors Henry J. McQuay, Eija Kalso, R. Andrew Moore
Imprint Seattle : IASP Press, c2008
Edition 1st ed
Descript xv, 407 p. : ill. ; 24 cm


"Presents invited papers from the 6th IASP Research Symposium, Systematic Reviews and Meta-Analyses in Pain, held in Spain in September 2006, organized by the International Collaboration on Evidence-Based Critical Care, Anaesthesia and Pain (ICECAP). Describes systematic reviews and meta-analyses that estimate the efficacy and harm of interventions in clinical trials of pain medications"--Provided by publisher


I: Systematic reviews and meta-analyses -- Systematic reviews: are we getting it right yet? -- Managing potential publication bias -- Individual patient meta-analysis -- Industry bias -- Placebo and control event rate -- Adverse events -- Guidelines, guidance, and evidence -- Basic science systematic reviews -- II: Acute pain -- Treatment of postoperative pain: by procedure or by patient factors? -- Is opioid sparing clinically relevant? -- Challenges in practicing evidence-based perioperative medicine using systematic reviews: what we know, what is uncertain, and what we need to know -- What can we learn from evidence on the use of NSAIDs, coxibs, and paracetamol (Acetaminophen) for acute pain? -- Dose response -- III: Chronic pain -- Defining the importance of change in clinical trials of acute pain -- Chronic nonmalignant pain in the elderly: do opioids cause cognitive impairment? -- Clinical trials in pediatric pain -- Opioids in chronic noncancer pain: systematic reviews of efficacy and safety—What more is needed? -- Trial design of psychological treatments in chronic pain: what can we tell patients? -- Cannabinoids and analgesia, with special reference to neuropathic pain -- Epidemiology of chronic pain -- Cognitive-behavioral pain management: lessons learned -- IV: Cancer pain -- Trial design in cancer pain: oral opioids and the missing placebo -- What evidence do we have that the WHO ladder is effective in cancer pain? -- V: From evidence to practice -- What we have learned about trials from systematic reviews -- Risk: presentation and systematic reviews -- Randomized controlled trials for complex interventions? -- Evidence-based decision making: why is it so difficult to get from evidence to practice? -- Economics: delivering better health care? -- Pain ladders, systematic reviews, and trials -- Research translation for systematic reviews into community practice: the alberta HTA chronic pain ambassador program

Pain -- research Research design

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