Osteoporosis, a disease of bones that leads to an increased risk of fracture, It is a very serious condition that may occur in every elderly people especially in women after menopause. Once happen to elderly people, it causes more complication than many other. Interesting information, the mortality rate of osteoporosis is higher than that of cervical and breast cancer combined. The aim of this research is to measure the hardness of bone using femur and humerus bones of cadavers as models. The hardness of sixty femur and humerus bones from female and male with an average age of 73.2±9.3 years old were tested. The test results show that, The first plane of head femur bone consisting of position 5, 6, 7, and 8 is considered to be the neck areas, has the highest hardness value of 28.8±13.5 Newton/mm2. This region is responsible for supporting most of the body mass, it is therefore harder than any other regions. The second plane of head femur bone consisting of position 9, 10, 11 and 12 is considered to be the head areas, has the lowest hardness value of 20.8±10.1 Newton/mm2. These areas are very soft and used for friction reduction of ilium. While the first plane of humerus bone consisting of position 1 2 3 and 4, is considered to be a surgical neck area, has the highest hardness value of 25.3±11.9 Newton/mm2. This region is responsible for supporting most of the body mass, it is therefore harder than any other areas. The second plane of humerus bone consisting of position 5,6,7 and 8 is considered to be an anatomic neck area, has the lowest hardness value of 18.3±9.7 Newton/mm2. This areas is very soft and used for reducing the friction of glenoid. These data maybe used as guideline for surgeon so that appropriate precaution can be taken during to reduce bone fracture In addition, they may be used as experimental data for the validation of theoretical analysis using finite element computer software.