I: Pediatric sedation outside the operating room -- The history of sedation -- Procedural sedation: let's review the basics: the pediatrician's perspective -- Sedation policies, recommendations and guidelines across the specialties and continents -- Sedation scales and discharge criteria: how do they differ? which one to choose? do they really apply to sedation? -- Physiological monitoring for procedural sedation: the routine and beyond -- The pediatric airway: anatomy, challenges, and solutions -- Pediatric physiology: how does it differ from adults? -- Pharmacology and clinical application of sedatives, analgesics and adjuncts -- Pharmacokinetics and pharmacodynamics in the pediatric population -- Billing and reimbursement for sedation services -- II: Sedation models delivered by different specialties: a global voyage -- The pediatric hospital medicine service: models, protocols, and challenges -- The anesthesia directed sedation service: models, protocols, and challenges -- Sedation in the intensive care unit: challenges, outcomes and future strategies -- Sedation for pediatric gastrointestinal procedures -- Sedation in the emergency department: a complex and multifactorial challenge -- Sedation of pediatric patients for dental procedures -- Pediatric sedation: the european experience and approach -- Pediatric sedation in the underdeveloped third world: an african perspective: models, protocols, and challenges -- III: Safety in sedation -- Pediatric sedatives and the food and drug administration (FDA): challenges, limitations, and drugs in development -- Incidence and stratification of adverse events associated with sedation: is there a benchmark? -- Medicolegal risks and outcomes of sedation -- Designing a safe pediatric sedation service: adopting a new culture -- IV: Sedation into the twenty-second century -- Intravenous infusions for sedation: rationale, state of the art and future trends -- Usage of complementary and alternative medicine in pediatric sedation -- Future of pediatric sedation

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