I: General issues -- Epidemiology of esophageal and hypopharyngeal squamous cell carcinoma -- Classification and staging systems -- Preoperative work-up: conventional radiology, ultrasonography, CT scan, and MRI -- Preoperative work-up: esophagoGastroDuodenoScopy, tracheobronchoscopy, and endoscopic ultrasonography -- Preoperative work-up: PET and PET-CT -- Role of PET-CT in the prediction of response to neoadjuvant treatment -- Role of molecular biology in the prediction of response to neoadjuvant treatment -- Patient selection according to general condition and associated disease -- Esophageal cancer surgery: the importance of hospital volume -- II: Carcinoma of hypopharynx and cervical esophagus -- Surgical treatment: indications, early and long-term results, and disease recurrence -- Multimodal treatment: early and long-term results and recurrences -- III: Carcinoma of thoracic esophagus -- Neoadjuvant treatment -- Controversial issues in esophageal cancer: surgical approach and lymphadenectomy -- Treatment of resectable esophageal cancer: indications and long-term results -- Treatment of unresectable esophageal cancer: indications and long-term results -- Early results: morbidity, mortality, and the treatment of complications -- Treatment of recurrent and metastatic esophageal cancer -- Role of endoscopy in palliative treatment -- Follow-up and quality of life after esophagectomy -- IV: Operative techniques -- Carcinoma of thoracic and cervical esophagus: technical notes -- Minimally invasive esophagectomy: general problems and technical notes

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