Fundamental concepts : Introduction ; The friction of distance ; Agglomeration ; Markets ; Spatial interaction ; Resources and the environment ; The production technology -- The multiregional economy : Specialization and trade ; Interregional movements of labor and capital ; Polarization in the multiregional economy ; Scale economies and imperfect competition in the multiregional economy ; Unemployment and regional policy -- Location theory : Transportation and location ; Scale economies and input substitution ; Labor, rent, taxes and subsidies ; Interrelated location choices -- Markets for space : Agricultural land use ; Urban land use: the monocentric city ; Urban sprawl and the polycentric city -- Systems of cities : Urbanization ; City size distribution and urban hierarchies ; Central place theory ; Network urban systems -- Globalization and the knowledge economy : International trade and foreign direct investment ; The globalization of production systems ; The knowledge economy