Objectives: To study the clinical outcomes of medication therapy management for type 2 diabetic outpatients by the pharmacist at Nongbua hospital. Method: A total of 86 oral antidiabetic drug-treated type 2 diabetes patients were enrolled in the study during August 2010 to September 2011. Forty-three patients were randomized into the either study or control groups. Patients in the study group received medication therapy management (MTM), while the control group received regular service at diabetic clinic. MTM was carried out not only by a pharmacist who identified, resolved and prevented medication problems, and educated patients about disease and life-style modification but also by a nurse who followed the refill guideline that was drawn up by the pharmacist. Both groups were follow up at month 0, 1, 2 and 3. Result: There were no differences (P≥0.05) in patient demographic data and clinical outcomes. At the end of 3 month study, the patients in the study group had significantly decreased in A1C levels before and at the end of the study (from 8.6 ± 1.5% to 8.1 ± 1.2%; P<0.05) while A1C levels of patients in the control group increased non significantly (P≥0.05). The patients in the study group had significantly decreased in fasting plasma glucose levels at month 0, 1, 2 and 3 (P<0.05) and differed from the patients in the control group who had no significantly differences in fasting plasma glucose levels(P≥0.05). Patients in study group received MTM and the practice were done according to the guideline 167 (97.1%) out of 172 times. The pharmacist detected 114 drug related problems (DRPs) of which 104 DRPs were resolved by pharmacist , 10 DRPs were refered to physician and 97 were life-styled problems. Conclusion: At Nongbua hospital, medication therapy management for type 2 diabetic outpatients by the pharmacist increased patients compliance to treatment, solving or reducing the drug therapy problem and, consequently, improving patients’ glycemic control.
