ความชุกของการติดเชื้อคลามิเดียนิวโมนิอิและมัยโคพลาสมานิวโมนิอิในผู้ใหญ่ที่มีอาการไอเรื้อรัง / พรวิมล ลี้ทอง = Prevalence of Chlamydia pneumoniae and Mycoplasma pneumoniae in adults with prolonged cough / Pornvimol Leethong
Background : Pneumonia is an important cause of morbidity and mortality in all population worldwide. Chlamydia pneumoniae and Mycoplasma pneumoniae are the two most common atypical pathogens. The clinical course slow progression and have no specific symptoms. In Thailand, prevalence of C. pneumoniae and M. pneumoniae in adult with prolonged cough is not well established. This study aimed to evaluate the prevalence of two pathogens in adult with prolonged cough. Methods : We enrolled patients, 18 years old or older, with persisting cough more than 2 weeks at King Chulalongkorn Memorial Hospital. Nasopharyngeal swabs were taken for detection of nucleic acid by polymerase chain reaction and serology of C. pneumoniae and M. pneumoniae . Other baseline characteristics were collected. Results : 100 patients were recruited between June 2011 and February 2012. The participants had mean age of 58.26±15.95 years (28-87 years) and had mean prolonged-cough duration of 30.78±23.99 days (14-120 days). 6 patients had evidence of C. pneumoniae and 4 patients were diagnosed M. pneumoniae. The prevalence of C. pneumoniae and M. pneumoniae in adults with prolonged cough in Thailand from this study were 6% and 4%, respectively. Conclusions : In Thailand, C. pneumoniae and M. pneumoniae could be found in adult with prolonged cough so that physicians should increase awareness.
