Three dimensional scaffolds have been considered to have certain effets on cell growth and the secretion of extracellular matrices (ECMs.) In this study, a porous polycaprolactone (PCL) was fabricatd by solvent casting and particulate leaching method which incorporated with gelatn-hyaluronate-chondroitin sulfate on its surfae by freeze-drying method. To decline degradation rate, 1-etyl-3-(3-dimethylamino-propyl)-arbodiimine (EDC) was used in crosslink system. Scanning electron microscope (SEM) was used to investigate morphology. The scaffold showed pore size between 265-350 µm, which preferable for cell culturing. Chemical property analysis confirmed greater hydrophilicity than polycaprolactone surface. Scaffold with crosslinked glatin demonstratd better water absorption. Biocompatbility evaluation by human dental pulp cell indicated no toxicity of porous PCL saffolds and PCL with gelatin-hyaluronate-chondroitin sulfate. In addition, gelatn-hyaluronate-chondroitin sulfate on PCL scaffold also upported cell attachment.